Results 141 to 150 of about 17,943 (269)

Supplementary Tables 1-4 and Supplementary Figures S1 to S7; and Supplementary Materials and Methods from β-Arrestins Regulate Stem Cell-Like Phenotype and Response to Chemotherapy in Bladder Cancer

, 2023
Georgios Kallifatidis, Diandra K. Smith, Daley S. Morera, Jie Gao, Martin Hennig, James J. Hoy, Richard F. Pearce, Isha R. Dabke, Jiemin Li, Axel S. Merseburger, Markus A. Kuczyk, Vinata B. Lokeshwar, Bal L. Lokeshwar   +12 more
openalex   +1 more source

The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Alzheimer's disease (AD) and glioblastoma multiforme (GBM) are biologically distinct age‐related brain disorders with opposing clinical phenotypes. AD is characterised by progressive neurodegeneration and cognitive decline, whereas GBM is characterised by aggressive cellular proliferation and a poor prognosis.
Ana B. Caniceiro, Sofia P. Agostinho, Luiz F. Piochi, Nícia Rosário‐Ferreira, Irina S. Moreira   +4 more
wiley   +1 more source

C-edge loops of arrestin function as a membrane anchor

Nature Communications, 2017
The activity of G-protein-coupled receptors is regulated by their interaction with arrestins. Here the authors show that loops located on C-edge of arrestin-1 serve as a membrane anchor during the multi-step binding process that leads to a stable ...
Ciara C M. Lally, Brian Bauer, Jana Selent, Martha E Sommer   +3 more
doaj   +1 more source

GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision [PDF]

, 2022
Wesley B. Asher, Daniel S. Terry, G. Glenn Gregorio, Alem W. Kahsai, Alessandro Borgia, Bing Xie, Arnab Modak, Ying Zhu, Wonjo Jang, Alekhya Govindaraju, Li-Yin Huang, Asuka Inoue, Nevin A. Lambert, Vsevolod V. Gurevich, Lei Shi, Robert J. Lefkowitz, Scott C. Blanchard, Jonathan A. Javitch   +17 more
openalex   +1 more source

c‐Jun N‐terminal kinase 3 as a permissive regulator of β‐cell incretin responsiveness

Journal of Diabetes Investigation, EarlyView.
Yuji Yamazaki
wiley   +1 more source

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins [PDF]

, 2009
Parth Patwari, William A. Chutkow, Kiersten Cummings, Valerie L. R. M. Verstraeten, Jan Lammerding, Eric R. Schreiter, Richard Lee   +6 more
openalex   +1 more source

Investigation of adenosine A1 receptor mediated β-arrestin 2 recruitment using a split-luciferase assay [PDF]

, 2023
Luisa Saecker, Hanns Häberlein, Sebastian Franken   +2 more
openalex   +1 more source

MRAP2 Inhibits β-Arrestin-2 Recruitment to the Prokineticin Receptor 2

Current Issues in Molecular Biology
Melanocortin receptor accessory protein 2 (MRAP2) is a membrane protein that binds multiple G protein-coupled receptors (GPCRs) involved in the control of energy homeostasis, including prokineticin receptors.
Roberta Lattanzi, Ida Casella, Maria Rosaria Fullone, Daniela Maftei, Martina Vincenzi, Rossella Miele   +5 more
doaj   +1 more source

Arrestins [PDF]

, 2015
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
openaire   +1 more source

β-arrestin/connexin 43 complex anchors ERKs outside the nucleus: a pre-requisite for bisphosphonate anti-apoptotic effect mediated by CX43/ERK in osteocytes [PDF]

, 2016
Bisphosphonates (BPs) anti-fracture ef cacy may be due in part to inhibition of osteocyte apoptosis. This effect requires opening of con- nexin (Cx) 43 hemichannels and phosphoryla- tion of the extracellular signal regulated kinases (ERKs).
Bellido, Teresita, Gortazar, Arancha R., Plotkin, Lilian I.   +2 more
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