Results 1 to 10 of about 2,274 (109)

Animal arterivirus infections. [PDF]

Biomed Res Int, 2014
The arteriviruses (Family Arteriviridae, Genus Arterivirus) include an interesting group of enveloped positive stranded RNA viruses that infect domestic and wild animals and they share a strikingly similar genome organization and replication strategy to that of coronaviruses, but differ considerably in their genetic complexity and virion architecture ...
Archambault D, Balasuriya UB, Rowland RR, Yang H, Yoo D.   +4 more
europepmc   +4 more sources

Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it? [PDF]

Viruses, 2012
Regulatory T cells (T_regs) are a subset of T cells that are responsible for maintaining peripheral immune tolerance and homeostasis.
Tanya LeRoith, S. Michelle Todd, Thomas E. Cecere   +2 more
doaj   +4 more sources

Elucidating the enigmatic biology of arteriviruses through receptor discovery [PDF]

Journal of Virology
Arteriviruses are diverse +ssRNA viruses (Nidovirales Order; Arteriviridae Family) that infect a variety of mammals. Arterivirus infections can manifest in a variety of ways, ranging from viral hemorrhagic fever to persistent sub-clinical infection.
Adam L. Bailey
doaj   +2 more sources

Conserved Antagonization of Type I Interferon Signaling by Arterivirus GP5 Proteins [PDF]

Viruses
Arteriviruses can establish persistent infections in animals such as equids, pigs, nonhuman primates, rodents, and possums. Some Arteriviruses can even cause overt and severe diseases such as Equine Arteritis in horses and Porcine Reproductive and ...
Rissar Siringo Ringo, Amonrat Choonnasard, Tamaki Okabayashi, Akatsuki Saito   +3 more
doaj   +2 more sources

The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral replication, but stress granules are not induced by the infection [PDF]

Journal of Virology
Stress granules (SGs) are dynamic, cytoplasmic foci that form in response to environmental stresses, including viral infections, and function to restore cellular homeostasis by regulating mRNA translation, storage, and decay.
Ayisha A. Lavender, Oreoluwa Solanke, Hsin-Yao Tang, Hannah E. Peck, Daryll Vanover, Philip J. Santangelo, Margo A. Brinton   +6 more
doaj   +2 more sources

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells [PDF]

Proceedings of the National Academy of Sciences, 2013
Significance Many viruses encode proteases that cleave both viral and host substrates. Arteriviruses encode such a dual-specificity protease (PLP2) that removes ubiquitin from cellular proteins involved in host immunity. Based on a 3D structure of PLP2, we engineered the protease to have diminished deubiquitinating activity without affecting ...
Kasteren, P.B. van, Bailey-Elkin, B.A., James, T.W., Ninaber, D.K., Beugeling, C., Khajehpour, M., Snijder, E.J., Mark, B.L., Kikkert, M.   +8 more
openaire   +4 more sources

Toll-like Receptor 3 Activation Decreases Porcine Arterivirus Infection [PDF]

Viral Immunology, 2008
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that initiates infection in pulmonary alveolar macrophages (PAMs), elicits weak immune responses, and establishes a persistent infection. To understand the role of dsRNA intermediates in eliciting host immunity, we sought to determine if toll-like receptor-3 (TLR3), a well ...
Yongming, Sang, Chris R, Ross, Raymond R R, Rowland, Frank, Blecha   +3 more
openaire   +2 more sources

Heterodimerization of the Two Major Envelope Proteins Is Essential for Arterivirus Infectivity [PDF]

Journal of Virology, 2003
ABSTRACT The two major envelope proteins of arteriviruses, the membrane protein (M) and the major glycoprotein (GP 5 ), associate into a disulfide-linked heterodimer that is incorporated into the virion and has been assumed to be a prerequisite for virus assembly.
Eric J, Snijder, Jessika C, Dobbe, Willy J M, Spaan   +2 more
openaire   +2 more sources

Actinobacillus pleuropneumoniae Possesses an Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus [PDF]

, 2014
Pigs are often colonized by more than one bacterial and/or viral species during respiratory tract infections. This phenomenon is known as the porcine respiratory disease complex (PRDC). Actinobacillus pleuropneumoniae (App) and porcine reproductive and
Burciaga Nava, Jorge A., Gagnon, Carl A., Hernandez Reyes, Yenney, Jacques, Mario, Labrie, Josée, Lévesque, Cynthia, Provost, Chantale   +6 more
core   +17 more sources

Characterization of the microRNAome in porcine reproductive and respiratory syndrome virus infected macrophages. [PDF]

PLoS ONE, 2013
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a member of the arterivirus family, is the causative agent of Porcine Reproductive and Respiratory Syndrome (PRRS).
Julie A Hicks, Dongwan Yoo, Hsiao-Ching Liu   +2 more
doaj   +1 more source