Results 11 to 20 of about 2,312 (140)

Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions

Viruses, 2012
Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in ...
Ding Xiang Liu, Yanxin Zhong, Yong Wah Tan   +2 more
doaj   +3 more sources

Porcine Arterivirus Infection of Alveolar Macrophages Is Mediated by Sialic Acid on the Virus [PDF]

Journal of Virology, 2004
ABSTRACTRecently, we showed that porcine sialoadhesin (pSn) mediates internalization of the arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) in alveolar macrophages (Vanderheijden et al., J. Virol. 77:8207-8215, 2003). In rodents and humans, sialoadhesin, or Siglec-1, has been described as a macrophage-restricted molecule and to ...
Peter L, Delputte, Hans J, Nauwynck
openaire   +4 more sources

Novel Rodent Arterivirus Detected in the Brazilian Amazon. [PDF]

Viruses, 2023
da Paz TYB, Hernández LHA, Silva SPD, Silva FSD, Barros BCV, Casseb LMN, Guimarães RJPSE, Vasconcelos PFDC, Cruz ACR.   +8 more
europepmc   +2 more sources

Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
Abstract Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19 complications. Precisely, these food additives strengthen the overall COVID treatment and enhance the immunity of a person. Such compounds have been used at a large scale, in almost every household due to their better affordability and easy access.
Keshav Raj Paudel, Vyoma Patel, Sukriti Vishwas, Saurabh Gupta, Sumit Sharma, Yinghan Chan, Niraj Kumar Jha, Jesus Shrestha, Mohammad Imran, Nisha Panth, Shakti Dhar Shukla, Saurav Kumar Jha, Hari Prasad Devkota, Majid Ebrahimi Warkiani, Sachin Kumar Singh, Md Khadem Ali, Gaurav Gupta, Dinesh Kumar Chellappan, Philip M. Hansbro, Kamal Dua   +19 more
wiley   +1 more source

Antiviral Effects of Heparan Sulfate Analogue‐Modified Two‐Dimensional MXene Nanocomposites on PRRSV and SARS‐CoV‐2

Advanced NanoBiomed Research, Volume 2, Issue 10, October 2022., 2022
Heparan sulfate analogue (sodium 3‐mercaptopropane sulfonate, MPS) modified MXene nanocomposites (Ti3C2‐Au‐MPS) are successfully synthesized, which can strongly inhibit porcine reproductive and respiratory syndrome virus (PRRSV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pseudovirus.
Ting Tong, Wantao Tang, Shaobo Xiao, Jiangong Liang   +3 more
wiley   +1 more source

Recent insights into the structure and function of coronavirus ribonucleases

FEBS Open Bio, Volume 12, Issue 9, Page 1567-1583, September 2022., 2022
Coronaviruses encode two ribonucleases: Nsp14, an exonuclease, and Nsp15, an endonuclease. This review covers the latest structures of SARS‐CoV‐2 Nsp14 and Nsp15 and discusses insights into nuclease functions and progress towards therapeutic inhibitors. The viral particle was generated using BioRender.
Meredith N. Frazier, Amanda A. Riccio, Isha M. Wilson, William C. Copeland, Robin E. Stanley   +4 more
wiley   +1 more source

Escaping the Lion’s Den: redirecting autophagy for unconventional release and spread of viruses

The FEBS Journal, Volume 288, Issue 13, Page 3913-3927, July 2021., 2021
RNA virus progenies undergo secretion and spread via multiple pathways. We highlight recent evidence on the autophagosome‐derived unconventional route. The inner membrane of these organelles can either disintegrate to release free virions or stay intact to release populations of virions in membrane‐bound forms, which are then internalized into ...
Qi Wen Teo, Sophie Wilhelmina van Leur, Sumana Sanyal   +2 more
wiley   +1 more source

Disulfide Linkages Mediating Nucleocapsid Protein Dimerization Are Not Required for Porcine Arterivirus Infectivity [PDF]

Journal of Virology, 2012
ABSTRACT The nucleocapsid (N) proteins of the North American (type II) and European (type I) genotypes of porcine reproductive and respiratory syndrome virus (PRRSV) share only approximately 60% genetic identity, and the functionality of N in both genotypes, especially its role in virion assembly, is still poorly understood.
Zhang R, Chen C, Sun Z, Tan F, Zhuang J, Tian D, Tong G, Yuan S.   +7 more
openaire   +3 more sources

The Functional Deubiquitinating Enzymes in Control of Innate Antiviral Immunity

Advanced Science, Volume 8, Issue 2, January 20, 2021., 2021
This review systematically summarizes the role and mechanisms of deubiquitinating enzymes (DUBs) in regulating innate antiviral signaling via the Toll‐like receptors (TLRs), RIG‐I like receptors (RLRs), and cyclic GMP‐AMP synthase (cGAS). The role of viral DUBs counteracting host immune responses is also concluded.
Zhi Zong, Zhengkui Zhang, Liming Wu, Long Zhang, Fangfang Zhou   +4 more
wiley   +1 more source

Epizootiological and diagnostic significance of porcine reproductive and respiratory syndrome control [PDF]

Veterinarski Glasnik, 2002
The porcine reproductive and respiratory syndrome (PRRS) is a new viral disease in swine, designated exclusively under the acronym PRRS by the European Commission in 1991.
Radojičić Biljana, Đuričić Bosiljka, Gagrčn M.   +2 more
doaj   +1 more source