Results 81 to 90 of about 29,733 (246)

A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia. [PDF]

, 2007
OBJECTIVES: To compare the efficacy and tolerability of dihydroartemisinin-piperaquine (DHA-PQP) with that of a 3-day regimen of mefloquine and artesunate (MAS3) for the treatment of uncomplicated falciparum malaria in Cambodia.
Ashley, Ashley, Brockman, Chatterjee, Denis, Ezedinachi, Karunajeewa, Krudsood, Newcombe, Nosten, Piaggio, Price, Smithuis, Ter Kuile, Tran, WHO, Yeung   +16 more
core   +2 more sources

Guillain–Barré Syndrome Following Malaria: A Rare Case Report From Rural Ethiopia and Literature Review

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Guillain–Barré syndrome (GBS) is an acute immune‐mediated polyradiculoneuropathy often triggered by infections. Malaria, a common parasitic disease in endemic regions, has rarely been associated with GBS. We report a case of a 21‐year‐old male from rural Ethiopia who developed GBS following Plasmodium vivax malaria.
Hayatu Awel Abdela, Numeri Husein Kimo, Tamirat Godebo Woyimo   +2 more
wiley   +1 more source

Simultaneous Spectrophotometric Estimation of Artesunate and Mefloquine

Journal of Chemistry, 2013
A simple, rapid, precise, and accurate UV-visible spectrophotometric method has been developed for the simultaneous determination of Artesunate in combination with Mefloquine. For developing the method, methanol was used as a solvent.
T. M. Kalyankar, R. B. Kakade, M. S. Attar, A. R. Kamble   +3 more
doaj   +1 more source

Reaction of N‐Ferrocenylcarbamates with Nitric Oxide: An Application for Detection of Inflammatory Sites In Vivo

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
Nitric oxide induces decomposition of electron‐deficient aminoferrocene drugs 4 with formation of oxime 7, which is derived from the upper cyclopentadienyl ligand. Drugs 4 are not responsive to hydrogen peroxide. Based on the latter reaction, the fluorogenic probes are developed for detecting NO in cells and inflammation in vivo.
Roman Selin, Hülya Gizem Özkan, Galyna Bila, Rostyslav Bilyy, Andriy Mokhir   +4 more
wiley   +1 more source

Costing Artemisinin-based Combination Therapy for Malaria in Tanzania [PDF]

, 2005
Malaria continues to be a major contributor to the burden of disease in Tanzania, with a prevalence of 33.39 percent nationally. As antimalarial resistance to sulfadoxine-pyrimethamine in Tanzania continues to grow, the government is in the process of ...
Derriennic, Yann, Wolf, Katherine
core  

Stimulation of Suicidal Erythrocyte Death by Artesunate

Cellular Physiology and Biochemistry, 2014
Background: The artemisinin derivative artesunate is effective in the treatment of severe malaria and is considered for the treatment of malignancy. Artesunate triggers tumor cell apoptosis, an effect at least in part mediated by mitochondria.
Kousi Alzoubi, Salvatrice Calabrò, Rosi Bissinger, Majed Abed, Caterina Faggio, Florian Lang   +5 more
doaj   +1 more source

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections. [PDF]

, 2012
BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.
Khairnar, K, Krishna, S, Lau, R, Lepore, R, Pillai, DR, Staines, HM, Via, A   +6 more
core   +1 more source

Oligochitosan Conjugates of the Antimalarials Dihydroartemisinin and Lumefantrine: Synthesis, Stability, Cell Viability, and Antiplasmodial Studies

Applied Research, Volume 4, Issue 5, October 2025.
Schematic representation of orally administered antimalarial–oligochitosan conjugates. The mucoadhesive properties of oligochitosan facilitate enhanced drug absorption across the intestinal epithelium (Image created in BioRender.com & Microsoft 365 PowerPoint).
William Matshe, Sindisiwe Mvango, Rudzani Malabi, Asongwe Tantoh, Charlene Andraos, Ibukun Famuyide, Lyndy McGaw, Sooraj Baijnath, Lynne Pilcher, Mohammed Balogun   +9 more
wiley   +1 more source

Generalized Tetanus Associated With Malaria and Probable Meningitis in a 4‐Year‐Old Patient: A Case Report in Limbe Regional Hospital, Cameroon

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Tetanus is a life‐threatening disease preventable by immunization through vaccines. In resource‐limited settings, its association with other acute infections should be managed cautiously. A 4‐year‐old unvaccinated male was referred from a nearby hospital for better management of severe malaria and probable enteric fever, after presenting there
Christian Damien Tchuisseu Ngapjang, Christian Fotso, Ronald Gobina, Philippe Albert Lingo, Quincy‐Jones Shumbang Tchumukong, Bertold Brecht Kouam, Marc Effila, Emelinda Berinyuy Nyuydzefon, Verla Vincent Siysi   +8 more
wiley   +1 more source

Immunoinformatics‐Based Multi‐Epitope Vaccine Design Against P. falciparum‐Causing Malaria: A Computational Approach

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aim Malaria is an infectious disease that affects people in Africa, and other parts of the world by the millions. Despite the effectiveness of artemisinin‐based combination therapies against the disease, current findings on possible Plasmodium resistance to artemisinin warrants an exploration of new treatment options. This study
Amma Aboagyewa Larbi, Caleb Mensah, Rebecca Korankye, Andrew Appiah Darkwah, Esther Boakye Agyemang, Isaac Yao Ayikpah, Alexander Kwarteng   +6 more
wiley   +1 more source