Results 21 to 30 of about 9,974 (243)

Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis

open access: yesAsian Journal of Pharmaceutical Sciences
Flare and multiple recurrences pose significant challenges in gouty arthritis. Traditional treatments provide temporary relief from inflammation but fail to promptly alleviate patient pain or effectively prevent subsequent recurrences.
Rui Wang   +10 more
doaj   +2 more sources

Advances in the study of gut microecology and mechanisms of hyperuricemia and gouty arthritis [PDF]

open access: yesFrontiers in Immunology
Gouty arthritis is a metabolic disorder caused by purine metabolism dysregulation, characterized by monosodium urate crystal deposition in and around joints, triggering acute articular inflammation via NLRP3 inflammasome activation and IL-1β-mediated ...
Youliang Zhang   +15 more
doaj   +2 more sources

Therapeutic Effect of Polygonum multiflorum Extract on Gouty Arthritis in Rats [PDF]

open access: yesBIO Web of Conferences
Objective: The investigation of the efficacy of Polygonum multiflorum extract on gouty arthritis in rats. Method: Thirty male SD rats were randomly divided into blank control group, gouty arthritis model group, colchicine group, low, medium, and high ...
Tan Jinyi, Liu Qihang, He Lian
doaj   +2 more sources

Targeting Neutrophil Extracellular Traps in Gouty Arthritis: Insights into Pathogenesis and Therapeutic Potential

open access: yesJournal of Inflammation Research
Cantao Li,* Chenxi Wu,* Fenfen Li, Wenjing Xu, Xiaoxi Zhang, Yan Huang, Daozong Xia School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to ...
Fenfen Li, Xiaoxi Zhang, Daozong Xia
exaly   +2 more sources

Older age and diclofenac are associated with increased risk of upper gastrointestinal bleeding in gout patients [PDF]

open access: yesPeerJ, 2021
Background Gouty arthritis is a disease of global burden in which defective metabolism of uric acid causes arthritis. Gouty arthritis or medications used for its treatment may lead to uric acid-associated complications such as upper gastrointestinal ...
Wan Syamimee Wan Ghazali   +4 more
doaj   +2 more sources

Vertebrae Destruction with Cauda Equina Syndrome Secondary to Spinal Gouty Arthritis: A Case Report [PDF]

open access: yesMalaysian Orthopaedic Journal, 2020
Gouty arthritis commonly affects peripheral joints and is associated with hyperuricaemia. Spinal manifestations of gouty arthritis are not common, and majority of published articles worldwide were case reports.
Thuraikumar K, Wan KL, Ong KL, Lim SW
doaj   +1 more source

Correlation analysis of serum TLR4 protein levels and TLR4 gene polymorphisms in gouty arthritis patients.

open access: yesPLoS ONE
ObjectiveThe Toll-like receptor (TLR) 4-mediated nuclear factor kappa B (NF-κB) signaling pathway regulates the production of inflammatory factors and plays a key role in the pathogenesis of gouty arthritis.
Lu Liu   +6 more
doaj   +2 more sources

Lagotis brachystachya maxim attenuates chronic alcoholic liver injury combined with gouty arthritis in rats via its anti-inflammatory activity

open access: yesFrontiers in Pharmacology, 2022
Lagotis brachystachya Maxim, a common herb in Tibetan medicine, is mainly used to treat pneumonia, hepatitis, yellow water disease (gouty arthritis). Since long-term heavy drinking is also a risk factor for gouty arthritis, the present study aimed to ...
Min-Xia Guo   +7 more
doaj   +1 more source

Phospholipase A2 regulates autophagy in gouty arthritis: proteomic and metabolomic studies

open access: yesJournal of Translational Medicine, 2023
Background Acute gouty arthritis is inflammatory joint arthritis. Gouty arthritis (GA) involves multiple pathological processes. Deposition of joints by monosodium urate (MSU) crystals has been shown to play a critical role in the injury process.
Weili Fu, Minghao Ge, Jian Li
doaj   +1 more source

Comparison of MR Findings between Patients with Septic Arthritis and Acute Gouty Arthritis of the Knee

open access: yes대한영상의학회지, 2022
Purpose To compare the MR findings of septic and acute gouty arthritis of the knee joint. Materials and Methods This retrospective study included patients who underwent knee MRI for septic or gouty arthritis at our hospital between October 2012 and ...
Su Young Yun   +3 more
doaj   +1 more source

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