Glyburide inhibits the Cryopyrin/Nalp3 inflammasome [PDF]
Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-1 beta (IL-1 beta) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes triggered by microbial ligands, danger-associated molecular patterns
Mohamed Lamkanfi +43 more
core +2 more sources
Bio‐Propelled Stomatocyte Nanomotors with Glutathione‐Responsiveness for Osteoarthritis Treatment
Glutathione (GSH)‐responsive stomatocyte nanomotors with encapsulated MTX utilize oxygen to achieve autonomous motion and undergo GSH‐induced dissociation, enhancing cellular uptake, tissue penetration, and MTX release within the osteoarthritis (OA) region, thereby improving therapeutic efficacy.
Jianhong Wang +12 more
wiley +2 more sources
Physio-balneotherapy factors in the complex treatment of patients with gouty arthritis at the sanatorium stage of rehabilitation [PDF]
Purpose: to analyze and summarize the main approaches to the appointment of the main physiotherapeutic and balneological factors in the complex treatment of patients with gouty arthritis in the conditions of sanatorium treatment.
Tеtіana Ananіeva
doaj +1 more source
We investigated the functions of microRNAs in the therapeutic effects of noni (Morinda citrifolia L.) fruit juice on mouse models of acute gouty arthritis induced with monosodium urate (MSU). Compared with the model group (treated with MSU), mice in both
Xiaohong Li +12 more
doaj +1 more source
Tophaceous Gout Causing Atlanto-Axial Subluxation Mimicking Rheumatoid Arthritis: A Case Report
This is a case report of an extremely rare condition of atlanto-axial subluxation secondary to gouty arthritis, which mimicked rheumatoid arthritis at presentation. Gouty arthritis involving the spine is a rare condition.
NN Wazir, V Moorthy, A Amalourde, HH Lim
doaj +1 more source
Autoinflammatory Features in Gouty Arthritis [PDF]
In the panorama of inflammatory arthritis, gout is the most common and studied disease. It is known that hyperuricemia and monosodium urate (MSU) crystal-induced inflammation provoke crystal deposits in joints. However, since hyperuricemia alone is not sufficient to develop gout, molecular-genetic contributions are necessary to better clinically frame ...
Galozzi, Paola +4 more
openaire +3 more sources
An unusual location of gouty panniculitis: A case report. [PDF]
Gouty panniculitis, characterised by the deposition of monosodium urate crystals in subcutaneous tissue, is a rare clinical manifestation of gout. The case of a 67-year-old man is reported, who presented an erythematous nodule on the upper part of the ...
Brunel, C. +5 more
core +1 more source
Risk Factors in the Incidence of Gouty Arthritis in Masohi Town, Central Maluku Regency in 2010
The gouty arthritis incidence rate in Masohi Townof Central Maluku Regency is 54 people based on the data from the general hospital in Masohi. The aim of study was to find out the risk factor in the incidence of gouty arthritis in Masohi Town of Central ...
Bellytra Talarima +2 more
doaj +1 more source
Effect of nanoparticles on gouty arthritis: a systematic review and meta-analysis
Objective The purpose of this study was to explore the effects of nanoparticles on gouty arthritis, and to provide evidence for the preclinical application of nanoparticles in gouty arthritis and ideas for nanomedicine improvement for nanoparticle ...
Ruiting Zhu +9 more
doaj +1 more source
Risk Factors in the Incidence of Gouty Arthritis in Masohi Town, Central Maluku Regency in 2010 [PDF]
The gouty arthritis incidence rate in Masohi Townof Central Maluku Regency is 54 people based on the data from the general hospital in Masohi. The aim of study was to find out the risk factor in the incidence of gouty arthritis in Masohi Town of ...
Amiruddin, R. (Ridwan) +2 more
core +1 more source

