Results 51 to 60 of about 9,207 (164)

Cell-based in vitro hemoassay for evaluation of NLRP3-inflammasome activity

Медицинская иммунология
Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3.
N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova   +8 more
doaj   +1 more source

CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis

Nature Communications
Gouty arthritis evokes joint pain and inflammation. Mechanisms driving gout pain and inflammation remain incompletely understood. Here we show that CXCL5 activates CXCR2 expressed on nociceptive sensory neurons to drive gout pain and inflammation.
Chengyu Yin, Boyu Liu, Zishan Dong, Sai Shi, Chenxing Peng, Yushuang Pan, Xiaochen Bi, Huimin Nie, Yunwen Zhang, Yan Tai, Qimiao Hu, Xuan Wang, Xiaomei Shao, Hailong An, Jianqiao Fang, Chuan Wang, Boyi Liu   +16 more
doaj   +1 more source

Correlation analysis of serum TLR4 protein levels and TLR4 gene polymorphisms in gouty arthritis patients.

PLoS ONE
ObjectiveThe Toll-like receptor (TLR) 4-mediated nuclear factor kappa B (NF-κB) signaling pathway regulates the production of inflammatory factors and plays a key role in the pathogenesis of gouty arthritis.
Lu Liu, Shuang He, Lin Jia, Hua Yao, Dan Zhou, Xiaobin Guo, Lei Miao   +6 more
doaj   +1 more source

Clinical Application of Acupuncture and Moxibustion to the Treatment of Gouty Arthritis and Analysis on Their Therapeutic Effects

针刺研究, 2009
In the present paper,the authors make a summary on the clinical application of acu-moxibustion therapy in the treatment of gouty arthritis in recent 10 years.Acupuncture needles often used are filiform needle,red-hot needle,moxibustion-warmed needle and ...
LIN Cai-xia, MA Hui-fang, MA Wen-zhu, ZHOU Pei-juan1   +3 more
doaj   +2 more sources

Obesity, Echocardiographic Changes and Framingham Risk Score in the Spectrum of Gout: A Cross-Sectional Study

The Turkish Journal of Gastroenterology, 2019
Objectives: This study aims to establish cardiovascular risk in obese and non-obese patients in stages of gout by using Framingham risk score (FRS) and transthoracic echocardiography.
Rada GANCHEVA, Atanas KOUNDURDJIEV, Mariana IVANOVA, Todor KUNDURZHIEV, Zlatimir KOLAROV   +4 more
doaj  

Correction: Qingzhu granule mitigates acute gouty arthritis through HIF-1a-dependent glycolytic metabolic reprogramming of M1 macrophages. [PDF]

Front Immunol
Qi Y, Li W, Wang Q, Zhou S, Li Y, Li L.
europepmc   +1 more source

SSGJ-613 Alleviates Pain and Reduces the Risk of Acute Flares in Patients With Gout: A Randomized, Double-Blind, Phase II Study. [PDF]

Int J Rheum Dis
Xue Y, Zhu X, Zhang B, Li Y, Gou W, Dai L, Zhang N, Tang L, Zhang Z, Dong L, Yang X, Xu J, Li Z, Yang J, Lou J, Liu Y, Zou H.   +16 more
europepmc   +1 more source

Application of a Novel Ultrasound Scoring System in Assessing Disease Activity in Gouty Arthritis. [PDF]

J Inflamm Res
Chen S, Lin W, Lv G, Lai Z, Yang Q, Cai X.   +5 more
europepmc   +1 more source

Ulcerated Achilles Lesion Revealing Extensive Gouty Tophi in a Patient Under Chemotherapy. [PDF]

Int J Rheum Dis
Vougiouklakis G, Alexakis K, Christodoulou S, Fotsitzoudis C, Toulkeridis G, Agouridis AP.   +5 more
europepmc   +1 more source

Deep learning-based multiclass classification for the diagnosis of hand arthritis on digital radiography: a multicenter study. [PDF]

Front Med (Lausanne)
Deng C, Yan D, Tang C, Deng X, Li C, Chen X, Deng L, Wu Z.   +7 more
europepmc   +1 more source