Results 161 to 170 of about 36,412 (300)

Aryl hydrocarbon receptor (AHR) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Single‐Cell Transcriptome Atlas Reveals the Underlying Mechanism of Kynurenic Acid in the Regulation of Tumor Immune Microenvironment in Glioblastoma

Advanced Science, Volume 13, Issue 5, 27 January 2026.
KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen, Liming Sun, Jiajun Chen, Zi Ye, Xuqiang Zhu, Hongjiang Li, Lixin Wu, Guohua Zhao, Qinghao Zhang, Guangyi Jiang, Yuchen Ji, Yake Xue, Hongwei Li, Ruokun Chen, Hongwei Zheng, Rong Zeng, Dongming Yan, Yong Zhang, Xueyuan Li, Jing Yan   +19 more
wiley   +1 more source

Drug-Induced Glucose Metabolism Disorders: Role of Aryl Hydrocarbon Receptor. [PDF]

J Xenobiot
Grishanova AY, Perepechaeva ML.
europepmc   +1 more source

Molecular Interactions Governing the Rat Aryl Hydrocarbon Receptor Activities of Polycyclic Aromatic Compounds and Predictive Model Development

Lingmin Jin, Bangyu Chen, Guangcai Ma, Xiaoxuan Wei, Haiying Yu   +4 more
openalex   +1 more source

Cancer-promoting and Inhibiting Effects of Dietary Compounds: Role of the Aryl Hydrocarbon Receptor (AhR)

, 2014
Joann B. Powell Maryam Ghotbaddini
openalex   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Recombinant expression of aryl hydrocarbon receptor for quantitative ligand-binding analysis

, 2008
Ming Qi Fan, Alex Bell, David Bell, Sally Clode, A. R. Fernandes, Paul M.D. Foster, Jeffrey R. Fry, Tao Jiang, George Loizou, Alan D. MacNicoll, Brian G. Miller, Martin Rose, Osama A. Shaikhomar, Lang Tran, Shaun White   +14 more
openalex   +2 more sources

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

The absence or the pharmacological blockade of the aryl hydrocarbon receptor promotes neuroprotection in the hippocampus after an ischemic insult. [PDF]

PLoS One
Castañeda-Arellano R, García-Lara L, Angeles-López QD, Pérez-Severiano F, Elizondo-Azuela G, Dueñas-Jimenez SH, González-Pozos S, Aguilar-García IG, Segovia J.   +8 more
europepmc   +1 more source

The microbiota–gut–brain axis in mild cognitive impairment and Alzheimer's disease: a scoping review of human studies

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Alzheimer's disease (AD) is projected to become the highest‐burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut microbiomes in mild cognitive impairment (MCI) and AD included dietary and probiotic interventions.
Alison Warren, Zan Wynia, Patrick G. Corr, Mershad Fahim Devin, Zeynep Celikkol, Lindsey Gordon, Mina Farah, Michaela Karam, Daniel Villarreal, Scott A. Jackson, Leigh A. Frame   +10 more
wiley   +1 more source