Results 91 to 100 of about 23,969 (258)
The catalytic ortho-arylation of tyrosine
, 2009 The rhodium-catalysed direct ortho-arylation of protected racemic 2-tert-butyl tyrosine has been developed. The subsequent removal of the tert-butyl group yields the 2-arylated tyrosine which can undergo further rhodium-based arylation at the 6-position.
Webster, Ruth L. +7 more
core +1 more source
Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1
EcoEnergy, EarlyView.A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang +9 more
wiley +1 more source
Electrocatalytic Polarity Inversion of Azlactones: Access to α-Quaternary Amino Acids with Electron-Rich SOMOphiles. [PDF]
Angew Chem Int Ed EnglElectrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Rodríguez P +6 more
europepmc +3 more sources
Selective C-Arylation of Free (NH)-Heteroarenes via Catalytic C−H Bond Functionalization
, 2016 A new system for palladium-catalyzed arylation of a broad spectrum of free (NH)-heteroarenes has been developed (indole, pyrrole, pyrazole, 2-phenylimidazole, imidazole, benzimidazole, and purine). Remarkable selectivity has been achieved in the presence
Dalibor Sames (1432975) +1 more
core +1 more source
European Journal of Inorganic Chemistry, EarlyView.Rollover cyclometalation is a distinctive variant of classical cyclometalation where a chelated heterocyclic ligand undergoes internal rotation, releasing one donor atom from coordination and subsequently activating a remote C─H bond with high regioselectivity.
Antonio Zucca, Maria I. Pilo
wiley +1 more source
Asymmetric Arylation of Ketone Enolates
, 2016 Asymmetric Arylation of Ketone ...
Jens Åhman (2985168) +4 more
core +1 more source
Navigating the Radical Oxo‐Functionalization of Alkenes Toward Ketones
European Journal of Organic Chemistry, EarlyView.Straightforward access to complex ketones in a single synthetic step: This Review surveys the latest advances in three‐component alkene 1,2‐oxo‐functionalizations. The opportunities unlocked by the so‐called single‐electron (1e–) logic, including access to a broad pool of radical precursors and carbonyl oxygen atom sources, are highlighted.
Mattia Lepori +3 more
wiley +1 more source
Nature CommunicationsSite-selective C(sp3)–H arylation is an appealing strategy to synthesize complex arene structures but remains a challenge facing synthetic chemists. Here we report the use of photoredox-mediated hydrogen atom transfer (HAT) catalysis to accomplish the ...
Jie Xu +5 more
doaj +1 more source
Diastereodivergent Construction of Octahydrophenanthridinone and Octahydrophenanthridine Cores
MoleculesDiastereodivergent synthesis of octahydrophenanthridinone and octahydrophenanthridine skeletons, structural motifs often found in biologically active natural products, is described.
Chunzhao Sun +3 more
doaj +1 more source
Palladium-catalyzed selective oxidative olefination and arylation of 2-pyridones
, 2012 Substrate-controlled selective oxidative olefination of N-protected 2-pyridones has been achieved under palladium catalysis. The 5-position selectivity was followed for N-protected simple pyridones.
李兴伟 +4 more
core +1 more source