Results 81 to 90 of about 22,861 (258)

Nickel-catalyzed switchable arylative/endo-cyclization of 1,6-enynes

Nature Communications
Carbo- and heterocycles are frequently used as crucial scaffolds in natural products, fine chemicals, and biologically and pharmaceutically active compounds.
Wenfeng Liu, Wei Li, Weipeng Xu, Minyan Wang, Wangqing Kong   +4 more
doaj   +1 more source

Direct arylation catalysis with chloro[8-(dimesitylboryl)quinoline-κN]copper(I)

Beilstein Journal of Organic Chemistry, 2016
We report direct arylation of arylhalides with unactivated sp2 C–H bonds in benzene and naphthalene using a copper(I) catalyst featuring an ambiphilic ligand, (quinolin-8-yl)dimesitylborane.
Sem Raj Tamang, James D. Hoefelmeyer
doaj   +1 more source

Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings

Beilstein Journal of Organic Chemistry, 2021
A wide range of derivatives with new pyrido[2,1-a]pyrrolo[3,4-c]isoquinoline skeleton was synthesized by free-radical intramolecular cyclization of o-bromophenyl-substituted pyrrolylpyridinium salts using the (TMS)3SiH/AIBN system.
Ivan P. Mosiagin, Olesya A. Tomashenko, Dar’ya V. Spiridonova, Mikhail S. Novikov, Sergey P. Tunik, Alexander F. Khlebnikov   +5 more
doaj   +1 more source

Transition metal-free synthesis of quinolino[2′,3′:3,4]pyrazolo[5,1-b]quinazolin-8(6H)-ones via cascade dehydrogenation and intramolecular N-arylation

, 2022
2-(2-Chloroquinolin-3-yl)-3-(arylamino)-2,3-dihydroquinazolin-4(1H)-one was converted to quinolino[2′,3′:3,4]pyrazolo[5,1-b]quinazolin-8(6H)-ones in the presence of KOtBu in DMSO at room temperature.
Zahra Tanbakouchian (6841619), Atefeh Nejatinezhad-Arani (9525458), Hoda Hamidi (9515602), Majid Mommahed Heravi (9225485), Morteza Shiri (9669851), Suhas A. Shintre (9507734), Neil Anthony Koorbanally (3725665), Mohammad Ali Zolfigol (619986)   +7 more
core   +1 more source

Site-selective α-C(sp3)–H arylation of dialkylamines via hydrogen atom transfer catalysis-enabled radical aryl migration

Nature Communications
Site-selective C(sp3)–H arylation is an appealing strategy to synthesize complex arene structures but remains a challenge facing synthetic chemists. Here we report the use of photoredox-mediated hydrogen atom transfer (HAT) catalysis to accomplish the ...
Jie Xu, Ruihan Li, Yijian Ma, Jie Zhu, Chengshuo Shen, Heng Jiang   +5 more
doaj   +1 more source

Access to Macrocycles with an endo Aryl Ether and an endo Aryl-Aryl Bond, Development and Application

CHIMIA, 2011
Macrocyclization methodologies allowing access to macrocycles having an endo aryl ether and an endo aryl–aryl bond, especially those based on an intramolecular SNAr reaction and the Suzuki-Miyaura reaction, are summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies are presented.
Wang, Qian, Zhu, Jieping
openaire   +6 more sources

Mechanistic study of enantioselective - alpha-arylation of ketone with diaryliodonium salt catalyzed with Cu and chiral bis-phosphinoxide

, 2023
reservedThis thesis work is focused on the mechanistic study of a Cu-based catalytic system for a stereoselective α-arylation of carbonyl compounds previously developed in our group. This system presents several interesting features as it exploits chiral
SARTORELLO, MATTIA
core  

Chromium(II)-catalyzed enantioselective arylation of ketones

Beilstein Journal of Organic Chemistry, 2016
The chromium-catalyzed enantioselective addition of carbo halides to carbonyl compounds is an important transformation in organic synthesis. However, the corresponding catalytic enantioselective arylation of ketones has not been reported to date. Herein,
Gang Wang, Shutao Sun, Ying Mao, Zhiyu Xie, Lei Liu   +4 more
doaj   +1 more source

Synthesis of 2,2,5-Trisubstituted 2H‑Pyrroles and 2,3,5-Trisubstituted 1H‑Pyrroles by Ligand-Controlled Site-Selective Dearomative C2-Arylation and Direct C3-Arylation

, 2019
Palladium-catalyzed site-selective dearomative C2-arylation of 2,5-diaryl-1H-pyrroles with aryl chlorides was accomplished, and a series of 2,2,5-triaryl-2H-pyrroles were synthesized.
Sakiko Fujiwara, Sakiko Fujiwara (7180421), Miyuki Yamaguchi (1814692), Kei Manabe (1814695), Miyuki Yamaguchi, Kei Manabe   +5 more
core   +1 more source

An easy direct arylation of 5-pyrazolones

Beilstein Journal of Organic Chemistry, 2013
A mild, efficient and catalytic ligand-free method for the direct arylation of 5-pyrazolones by Pd-catalyzed C–H bond activation is reported. The process smoothly proceeds and yields are moderate to excellent.
Hao Gong, Yiwen Yang, Zechao Wang, Chunxiang Kuang   +3 more
doaj   +1 more source