Results 71 to 80 of about 33,950 (227)
Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Benzyne arylation of oxathiane glycosyl donors
Beilstein Journal of Organic Chemistry, 2010 The arylation of bicyclic oxathiane glycosyl donors has been achieved using benzyne generated in situ from 1-aminobenzotriazole (1-ABT) and lead tetraacetate.
Martin A. Fascione, W. Bruce Turnbull
doaj +1 more source
Selectivity Control in the Palladium-catalyzed Cross-coupling of Alkyl Nucleophiles [PDF]
, 2016 Site-selectivity remains a major challenge in metal-catalyzed C–H bond functionalization. Most existing strategies rely on the introduction of a directing group or on the intrinsic reactivity of the substrate.
Baudoin, Olivier
core +2 more sources
Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives
Chemistry – A European Journal, EarlyView.Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome +6 more
wiley +1 more source
Journal of Chemistry, 2013 Phosphine-free palladium-catalyzed direct arylation of 2-phenyl-imidazo[1,2-a]pyridine has been developed with the concept of using silver(I) carboxylate.
Sridevi Kona +3 more
doaj +1 more source
Palladium-catalyzed selective α-arylation of ortho -bromoacetophenones [PDF]
, 2014 Synthesis of 1-(2-bromophenyl)-2-phenylethanones via an intermolecular Pd-catalyzed α-arylation of 1-(2-bromophenyl)ethanones is presented. The method relies on selective C-H activation (α-arylation) of relatively more reactive external iodo-arenes as ...
A, Gopi Krishna Reddy +2 more
core +1 more source
Pd‐Catalyzed C─C Bond Borylation of Biphenylenes Leading to Tri‐Ortho‐Substituted Biaryls
Chemistry – A European Journal, EarlyView.Palladium‐catalyzed ring‐opening C─C borylation of 1‐substituted biphenylenes yields a range of o,o,o′‐trisubstituted biaryls with two ortho‐boryl groups via selective cleavage of the least hindered C─C bond. The resulting diborylated products are readily amenable to sequential, site‐selective postfunctionalization.
Robyn V. Presland +5 more
wiley +1 more source
Nickel-catalyzed switchable arylative/endo-cyclization of 1,6-enynes
Nature CommunicationsCarbo- and heterocycles are frequently used as crucial scaffolds in natural products, fine chemicals, and biologically and pharmaceutically active compounds.
Wenfeng Liu +4 more
doaj +1 more source
Direct arylation catalysis with chloro[8-(dimesitylboryl)quinoline-κN]copper(I)
Beilstein Journal of Organic Chemistry, 2016 We report direct arylation of arylhalides with unactivated sp2 C–H bonds in benzene and naphthalene using a copper(I) catalyst featuring an ambiphilic ligand, (quinolin-8-yl)dimesitylborane.
Sem Raj Tamang, James D. Hoefelmeyer
doaj +1 more source
Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings
Beilstein Journal of Organic Chemistry, 2021 A wide range of derivatives with new pyrido[2,1-a]pyrrolo[3,4-c]isoquinoline skeleton was synthesized by free-radical intramolecular cyclization of o-bromophenyl-substituted pyrrolylpyridinium salts using the (TMS)3SiH/AIBN system.
Ivan P. Mosiagin +5 more
doaj +1 more source