Results 121 to 130 of about 2,541 (157)

Aptamer as a therapeutic agent for dengue infections. [PDF]

open access: yesVirol J
Mislan NAL   +6 more
europepmc   +1 more source

Comparative Analysis of Aptamer-Conjugated Chemical and Green Synthesized Gold Nanoparticles for Targeted Therapy in MCF-7 Cancer Cells. [PDF]

open access: yesAppl Biochem Biotechnol
Helal MW   +9 more
europepmc   +1 more source

Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins. [PDF]

open access: yesProc Natl Acad Sci U S A
Xie W   +8 more
europepmc   +1 more source
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Therapeutic applications of AS1411 aptamer, an update review

International Journal of Biological Macromolecules, 2020
Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus. However, in several cancers, nucleolin is highly expressed both intracellularly and on the cell surface. So, it is considered as a potential target for the diagnosis and cancer therapy.
Mohammad Ramezani   +2 more
exaly   +3 more sources

Corneal neovascularization is inhibited with nucleolin-binding aptamer, AS1411

Experimental Eye Research, 2020
Corneal neovascularization (CNV) is a common sight-threatening pathology that can be induced by a variety of inflammatory and angiogenic stimuli. Current CNV treatments include anti-inflammatory drugs and antibody-based inhibitors of vascular endothelial growth factor (VEGF).
OSCAR Vivanco-Rojas   +2 more
exaly   +3 more sources

Nucleolin Overexpression Confers Increased Sensitivity to the Anti-Nucleolin Aptamer, AS1411 [PDF]

open access: yesCancer Investigation, 2018
AS1411 is an antiproliferative DNA aptamer, which binds the ubiquitous protein, nucleolin. In this study, we show that constitutive overexpression of nucleolin confers increased sensitivity to the growth inhibitory effects of AS1411. HeLa cells overexpressing nucleolin have an increased growth rate and invasiveness relative to control cells.
Shelia Thomas   +2 more
exaly   +3 more sources

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