Results 151 to 160 of about 150,558 (259)

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, Volume 13, Issue 60, 28 October 2026.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

Reactive Oxygen Species as Central Coordinators of Organelle Stress and Tumor Radiosensitivity

open access: yesCell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Radiotherapy is a major modality for cancer treatment, but therapeutic responses vary substantially across tumor types and patients. Beyond direct DNA damage, radiation‐induced reactive oxygen species (ROS) are increasingly recognized as dynamic regulators of cellular stress responses.
Guangyu Ju   +7 more
wiley   +1 more source

Catalase (CAT) activity, hydrogen peroxide (H2O2), guaiacol peroxidase (GPX), ascorbate peroxidase (APX), malondialdehyde (MDA) and proline content in leaves harvested from TKS plants grown under different levels of drought stress.

open access: yes
Catalase (CAT) activity, hydrogen peroxide (H2O2), guaiacol peroxidase (GPX), ascorbate peroxidase (APX), malondialdehyde (MDA) and proline content in leaves harvested from TKS plants grown under different levels of drought stress.
Meisam Zargar (17827351)   +5 more
core   +1 more source

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton   +9 more
wiley   +1 more source

Comparative Proteomic Analysis Reveals the Ascorbate Peroxidase-Mediated Plant Resistance to Verticillium dahliae in Gossypium barbadense. [PDF]

open access: yesFront Plant Sci, 2022
Lu T   +12 more
europepmc   +1 more source

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States

open access: yesGlia, Volume 74, Issue 10, October 2026.
Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar   +3 more
wiley   +1 more source

Nitric Oxide (NO) Differentially Modulates the Ascorbate Peroxidase (APX) Isozymes of Sweet Pepper (Capsicum annuum L.) Fruits. [PDF]

open access: yesAntioxidants (Basel), 2022
González-Gordo S   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy