The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs [PDF]
Emerging Microbes and InfectionsAfrican swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Yao Li +14 more
doaj +3 more sources
Molecular Characterization of ASFV and Differential Diagnosis of Erysipelothrix in ASFV-Infected Pigs in Pig Production Regions in Cameroon [PDF]
Veterinary Sciences, 2022 African swine fever and swine erysipelas are two devastating diseases with similar manifestations ravaging the domestic pig industry. Only a single phylogenetic study has been carried out in Cameroon, and neither an extensive genotyping aimed at identifying the different serotypes nor has an appropriate differential diagnosis of different species of ...
Ebanja Joseph Ebwanga +2 more
openalex +4 more sources
Patterns of ASFV Transmission in Domestic Pigs in Serbia [PDF]
Pathogens, 2023 The first case of African swine fever in domestic pigs in Serbia was in 2019. The following year, the disease was confirmed in wild boar. Thenceforth, ASF has been continuously reported in both wild and domestic pigs. The outbreaks in domestic pigs could not be linked directly to wild boars, even though wild boars were endemically infected, and ...
Dimitrije Glišić +8 more
openalex +6 more sources
Dynamics of African swine fever virus (ASFV) infection in domestic pigs infected with virulent, moderate virulent and attenuated genotype II ASFV European isolates. [PDF]
Transboundary and Emerging Diseases, 2021 This study aimed to compare the infection dynamics of three genotype II African swine fever viruses (ASFV) circulating in Europe. Eighteen domestic pigs divided into three groups were infected intramuscularly or by direct contact with two haemadsorbent ASFVs (HAD) from Poland (Pol16/DP/ OUT21) and Estonia (Est16/WB/Viru8), and with the Latvian non-HAD ...
Carmina Gallardo +10 more
openalex +4 more sources
Interactome between ASFV and host immune pathway proteins
mSystems, 2023 African swine fever virus (ASFV) causes severe acute hemorrhagic disease with high mortality in domestic pigs but minimal or no symptoms to warthogs, for which the underlying mechanism remains elusive.
Qijun Wu +13 more
doaj +3 more sources
Evaluation of the Presence of ASFV in Wolf Feces Collected from Areas in Poland with ASFV Persistence [PDF]
Viruses, 2021 African swine fever (ASF), caused by a DNA virus (ASFV) belonging to genus Asfivirus of the Asfarviridae family, is one of the most threatening diseases of suids. During last few years, it has spread among populations of wild boars and pigs in countries of Eastern and Central Europe, causing huge economical losses.
Maciej Szewczyk +8 more
openalex +5 more sources
Establishment and Evaluation of a Multicolor Latex Microsphere-Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses. [PDF]
Transbound Emerg DisAfrican swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Chen J +13 more
europepmc +2 more sources
A Novel In-Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus-Specific IgM and IgG Antibodies. [PDF]
Transbound Emerg DisAfrican swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Wu P +4 more
europepmc +2 more sources
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics [PDF]
Frontiers in Immunology, 2022 African swine fever virus (ASFV) causes a lethal swine hemorrhagic disease and is currently responsible for widespread damage to the pig industry. The pathogenesis of ASFV infection and its interaction with host responses remain poorly understood. In this study, we profiled the temporal viral and host transcriptomes in porcine alveolar macrophages ...
Lin Lv +7 more
openalex +4 more sources
Reclassification of ASFV into 7 Biotypes Using Unsupervised Machine Learning [PDF]
Viruses, 2023 In 2007, an outbreak of African swine fever (ASF), a deadly disease of domestic swine and wild boar caused by the African swine fever virus (ASFV), occurred in Georgia and has since spread globally. Historically, ASFV was classified into 25 different genotypes.
Mark Dinhobl +8 more
openalex +4 more sources