Results 111 to 120 of about 10,002 (242)

The role of wild hosts (wild pigs and ticks) in the epidemiology of African swine fever in West Africa and Madagascar [PDF]

open access: yes, 2007
African swine fever (ASF) adversely affects pig production in Sub-Saharan Africa. In southern and eastern Africa, the virus is maintained in populations of wild pigs (Phacochoerus africanus) and soft ticks from the Genus Ornithodoros.
Akakpo, J.   +9 more
core  

MHC Class II–Alpha Chain Knockout Mice Support Increased Viral Replication That Is Independent of Their Lack of MHC Class II Cell Surface Expression and Associated Immune Function Deficiencies

open access: yes, 2015
MHCII molecules are heterodimeric cell surface proteins composed of an α and β chain. These molecules are almost exclusively expressed on thymic epithelium and antigen presenting cells (APCs) and play a central role in the development and function of CD4
Alsharifi, Mohammed   +4 more
core   +1 more source

Scanning transmission electron tomography to study virus assembly: Review for the retirement of Paul Walther

open access: yesJournal of Microscopy, Volume 299, Issue 3, Page 206-211, September 2025.
Abstract In this short and popular review, we summarise some of our findings analysing the replication cycles of large DNA viruses using scanning transmission electron tomography (STEM tomography) that we applied in the laboratory of Paul Walther. It is also a tribute to a very kind and expert scientist, who recently retired.
Susanne Wieczorek   +1 more
wiley   +1 more source

Study on the role of the sylvatic cycle of African swine fever in Senegal [PDF]

open access: yes, 2009
It is generally believed that African swine fever (ASF) virus in Sub-Saharan Africa is maintained in nature by warthogs (Phacochoerus africanus) and soft ticks from the genus Ornithodoros (Penrith et al., 2004).
Akakpo, A.J.   +6 more
core  

Identification of cepharanthine as an effective inhibitor of African swine fever virus replication

open access: yesEmerging Microbes and Infections
African swine fever virus (ASFV) causes highly contagious swine disease, African swine fever (ASF), thereby posing a severe socioeconomic threat to the global pig industry and underscoring that effective antiviral therapies are urgently required.
Chuanxiang Qi   +10 more
doaj   +1 more source

Enhancing DNA immunization by targeting ASFV antigens to SLA-II bearing cells

open access: yesVaccine, 2011
One of the main criticisms to DNA vaccines is the poor immunogenicity that they confer on occasions, at least in large animals. Confirming this theory, immunization with plasmid DNA encoding two African swine fever virus genes in frame (pCMV-PQ), failed in inducing detectable immune responses in pigs, while it was successful in mice.
Argilaguet, JM   +13 more
openaire   +6 more sources

Is Ornithodoros erraticus able to transmit the Georgia2007/1 African Swine Fever virus isolate to domestic pigs? [PDF]

open access: yes, 2015
Objective: African swine fever, one of the most devastating diseases affecting wild and domestic swine, is due to a large DNA virus, only member of the Asfarviridae family.
Bernard, Jennifer   +6 more
core  

Evaluation of Haematological and Immunological Parameters of the ASFV Lv17/WB/Rie1 Strain and Its Derived Mutant Lv17/WB/Rie1/d110-11L against ASFV Challenge Infection in Domestic Pigs [PDF]

open access: gold, 2023
Giulia Franzoni   +12 more
openalex   +1 more source

African swine fever virus transmission cycles in Central Europe: evaluation of wild boar-soft tick contacts through detection of antibodies against Ornithodoros erraticus saliva antigen. [PDF]

open access: yes, 2016
BACKGROUND African swine fever (ASF) is one of the most complex viral diseases affecting both domestic and wild pigs. It is caused by ASF virus (ASFV), the only DNA virus which can be efficiently transmitted by an arthropod vector, soft ticks of the ...
Beer, Martin   +6 more
core   +4 more sources

Detection and genetic characterization of African swine fever virus (ASFV) in clinically infected pigs in two districts in South Kivu province, Democratic Republic Congo [PDF]

open access: gold, 2021
Patrick N. Bisimwa   +5 more
openalex   +1 more source

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