Results 11 to 20 of about 9,601 (189)

Interactome between ASFV and host immune pathway proteins

mSystems, 2023
African swine fever virus (ASFV) causes severe acute hemorrhagic disease with high mortality in domestic pigs but minimal or no symptoms to warthogs, for which the underlying mechanism remains elusive.
Qijun Wu, Yingying Lei, Ya Zuo, Ji Zhang, Fenglin Guo, Weize Xu, Tanghui Xie, Dang Wang, Guiqing Peng, Xiangru Wang, Huanchun Chen, Zhenfang Fu, Gang Cao, Jinxia Dai   +13 more
doaj   +3 more sources

Duration of immunity following infection with moderately virulent ASFV [PDF]

PLoS Pathog
AbstractAfrican swine fever virus (ASFV) poses a significant threat to pork production and wild pig populations worldwide. The study assessed the long-term fate and immunity of animals recovering from a moderately virulent ASFV infection, following the principles of a duration of immunity study for live vaccines.
Virginia Friedrichs, Paul Deutschmann, Kerstin Wernike, Tessa Carrau, Martin Beer, Sandra Blome, Alexander Schäfer   +6 more
openaire   +2 more sources

The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs [PDF]

Emerging Microbes and Infections
African swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Yao Li, Yingnan Liu, Zhuyun Sun, Zhenhua Xie, Chuanwen Tian, Rongrong Wang, Jun Gao, Maomao Wang, Jingyi Liu, Heng Wang, Guihong Zhang, Jie Li, Dongdong Di, Lang Gong, Hongjun Chen   +14 more
doaj   +2 more sources

A review of some important viral diseases of wild boars [PDF]

Biotechnology in Animal Husbandry, 2021
Wild boars are one of the widest-ranging mammals worldwide and represent reservoirs for many important viruses. Disease outbreaks in domestic swine are often described as a consequence of contact with wild boars, and traditional rearing conditions are a ...
Nišavić Jakov, Radalj Andrea, Milić Nenad, Živulj Aleksandar, Benković Damir, Stanojković Aleksandar, Prošić Isidora   +6 more
doaj   +1 more source

Evaluation of the Presence of ASFV in Wolf Feces Collected from Areas in Poland with ASFV Persistence [PDF]

Viruses, 2021
African swine fever (ASF), caused by a DNA virus (ASFV) belonging to genus Asfivirus of the Asfarviridae family, is one of the most threatening diseases of suids. During last few years, it has spread among populations of wild boars and pigs in countries of Eastern and Central Europe, causing huge economical losses.
Maciej Szewczyk, Krzysztof Łepek, Sabina Nowak, Małgorzata Witek, Anna Bajcarczyk, Korneliusz Kurek, Przemysław Stachyra, Robert W. Mysłajek, Bogusław Szewczyk   +8 more
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Structures and Functional Diversities of ASFV Proteins [PDF]

Viruses, 2021
African swine fever virus (ASFV), the causative pathogen of the recent ASF epidemic, is a highly contagious double-stranded DNA virus. Its genome is in the range of 170~193 kbp and encodes 68 structural proteins and over 100 non-structural proteins. Its high pathogenicity strains cause nearly 100% mortality in swine.
Guoguo Wang, Mengjia Xie, Wei Wu, Zhongzhou Chen   +3 more
openaire   +3 more sources

Expression of a recombinant ASFV P30 protein and production of monoclonal antibodies

Open Veterinary Journal, 2023
Background: African Swine Fever (ASF) is an infectious disease that affects domestic pig and wild boar populations. The African Swine Fever Virus (ASFV) has a genome characterized by a very complex DNA (170-193 kb) that encodes for more than 200 ...
Rosrio Liberti, Claudia Colabella, Lucia Anzalone, Giulio Severi, Antonella Di Paolo, Cristina Casciari, Anna Beatrice Casano, Monica Giammarioli, Monica Cagiola, Francesco Feliziani, Antonio De Giuseppe   +10 more
doaj   +1 more source

Inhibition of African swine fever virus replication by β-glucan

Open Veterinary Journal, 2022
Background: African swine fever (ASF) is one of the most important diseases in pigs because of its effects on all ages and breeds. To date, the commercial vaccines and drugs for prevention of ASF are lacking in the market and the survival of ASFV in ...
Truong Anh Duc, Ha Thi Thanh Tran, Nhu Thi Chu, Huyen Thi Nguyen, Hoang Vu Dang, Nam Hoai Vu, Hans Lee, Fatimah Siti, Tinh Nguyen, Alexander de Leon, Andrew G Yersin   +10 more
doaj   +1 more source

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L

Viruses, 2022
African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending on the virus strain and the genetic background of the pigs infected.
Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Van Dung Nguyen, Pham Hào Quang, Quách Võ Ngôn, Ayushi Rai, Cyril G. Gay, Douglas Paul Gladue, Manuel Victor Borca   +10 more
openaire   +3 more sources

Analysis of the Clinical Course of Experimental Infection with Highly Pathogenic African Swine Fever Strain, Isolated from an Outbreak in Poland. Aspects Related to the Disease Suspicion at the Farm Level

Pathogens, 2020
This paper was aimed to characterize clinical signs and pathomorphological lesions in twenty-two pigs, infected intranasally by different doses of African swine fever virus (Pol18_28298_O111), isolated during the outbreak in a pig farm that occurred in ...
Marek Walczak, Jacek Żmudzki, Natalia Mazur-Panasiuk, Małgorzata Juszkiewicz, Grzegorz Woźniakowski   +4 more
doaj   +1 more source