Results 21 to 30 of about 10,002 (242)

Inhibition of African swine fever virus replication by β-glucan

Open Veterinary Journal, 2022
Background: African swine fever (ASF) is one of the most important diseases in pigs because of its effects on all ages and breeds. To date, the commercial vaccines and drugs for prevention of ASF are lacking in the market and the survival of ASFV in ...
Truong Anh Duc, Ha Thi Thanh Tran, Nhu Thi Chu, Huyen Thi Nguyen, Hoang Vu Dang, Nam Hoai Vu, Hans Lee, Fatimah Siti, Tinh Nguyen, Alexander de Leon, Andrew G Yersin   +10 more
doaj   +1 more source

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L

Viruses, 2022
African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending on the virus strain and the genetic background of the pigs infected.
Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Van Dung Nguyen, Pham Hào Quang, Quách Võ Ngôn, Ayushi Rai, Cyril G. Gay, Douglas Paul Gladue, Manuel Victor Borca   +10 more
openaire   +3 more sources

Novel mechanism of African swine fever virus protein regulating typeⅡinterferon signaling pathway

生物医学转化, 2022
African swine fever virus (ASFV) is a large DNA virus that is highly contagious and pathogenic in domestic pigs with a mortality rate up to 100%. However, how ASFV suppresses JAK-STAT1 signaling to evade the immune response remains unclear. In this study,
Zhang Jing, Li Dan, Zheng Haixue
doaj   +1 more source

Analysis of the Clinical Course of Experimental Infection with Highly Pathogenic African Swine Fever Strain, Isolated from an Outbreak in Poland. Aspects Related to the Disease Suspicion at the Farm Level

Pathogens, 2020
This paper was aimed to characterize clinical signs and pathomorphological lesions in twenty-two pigs, infected intranasally by different doses of African swine fever virus (Pol18_28298_O111), isolated during the outbreak in a pig farm that occurred in ...
Marek Walczak, Jacek Żmudzki, Natalia Mazur-Panasiuk, Małgorzata Juszkiewicz, Grzegorz Woźniakowski   +4 more
doaj   +1 more source

ASF -survivors’ sera do not inhibit African swine fever virus replication in vitro

Journal of Veterinary Research, 2022
African swine fever virus (ASFV) causes one of the most dangerous diseases of pigs and wild boar – African swine fever (ASF). Since its second introduction into Europe (in 2007), the disease has been spreading consistently, and now ASF-free European ...
Walczak Marek, Juszkiewicz Małgorzata, Szymankiewicz Krzesimir, Szczotka-Bochniarz Anna, Woźniakowski Grzegorz   +4 more
doaj   +1 more source

Genome sequences of five African swine fever virus genotype IX isolates from domestic pigs in Uganda [PDF]

, 2018
Complete genome sequences of five African swine fever virus isolates were determined directly from clinical material obtained from domestic pigs in Uganda.
Biek, Roman, Da Silva Filipe, Ana, Davison, Andrew J., Masembe, Charles, Mayega, Francis Johnson, Muwanika, Vincent B., Ogweng, Peter, Palmarini, Massimo, Sreenu, Vattipally B., Wilkie, Gavin S.   +9 more
core   +3 more sources

Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein

Drug Delivery, 2021
The African swine fever virus (ASFV) is a huge and complex DNA virus that can lead to the acute death of pigs and cause huge losses to the global swine industry.
Shunli Yang, Xinming Zhang, Yuying Cao, Shuo Li, Junjun Shao, Shiqi Sun, Huichen Guo, Shuanghui Yin   +7 more
doaj   +1 more source

Meat Exudate for Detection of African Swine Fever Virus Genomic Material and Anti-ASFV Antibodies

Viruses, 2021
African swine fever (ASF) is one of the most important viral diseases of pigs caused by the ASF virus (ASFV). The virus is highly stable over a wide range of temperatures and pH and can survive in meat and meat products for several months, leading to ...
Chukwunonso Onyilagha, Mikyla Nash, Orlando Perez, Melissa Goolia, Alfonso Clavijo, Juergen A. Richt, Aruna Ambagala   +6 more
doaj   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these
Keshan Zhang, Bo Yang, Chaochao Shen, Ting Zhang, Yu Hao, Dajun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, Hong Tian, Fan Yang, Yi Ru, Wei Jun Cao, Jianhong Guo, Jijun He, Haixue Zheng, Xiangtao Liu   +19 more
doaj   +1 more source

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

Pathogens, 2020
African swine fever (ASF) poses a severe threat to the global pig industry for which currently there is no available vaccine. The aetiological ASF virus (ASFV) has a predilection for cells of the myeloid lineage, however little is known about its ...
Giulia Franzoni, Elisabetta Razzuoli, Silvia Dei Giudici, Tania Carta, Grazia Galleri, Susanna Zinellu, Mauro Ledda, Pierpaolo Angioi, Paola Modesto, Simon P. Graham, Annalisa Oggiano   +10 more
doaj   +1 more source