Results 31 to 40 of about 10,002 (242)

African Swine Fever Virus (ASFV): Immunity and Vaccine Development

Vaccines, 2023
African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...]
Kiramage Chathuranga, Jong-Soo Lee
openaire   +3 more sources

Quantitative approach for the risk assessment of African swine fever and Classical swine fever introduction into the United States through legal imports of pigs and swine products. [PDF]

, 2017
The US livestock safety strongly depends on its capacity to prevent the introduction of Transboundary Animal Diseases (TADs). Therefore, accurate and updated information on the location and origin of those potential TADs risks is essential, so preventive
Burton, Kenneth, Herrera-Ibatá, Diana María, Martínez-López, Beatriz, Mur, Lina, Quijada, Darla   +4 more
core   +14 more sources

Host Responses to Live-Attenuated ASFV (HLJ/18–7GD)

Viruses, 2022
African swine fever (ASF) is a highly contagious and fatal disease caused by the African swine fever virus. Recently, the multigene family and CD2v gene-deleted ASF vaccine candidate HLJ/18-7GD was found to be safe and effective in laboratory and clinical trials.
Yuqin Fan, Weiye Chen, Chenggang Jiang, Xianfeng Zhang, Ying Sun, Renqiang Liu, Jingfei Wang, Decheng Yang, Dongming Zhao, Zhigao Bu, Xijun He   +10 more
openaire   +3 more sources

The 24.5-kb Left Variable Region Is Not a Determinant for African Swine Fever Virus to Replicate in Primary Porcine Alveolar Macrophages

Viruses, 2022
African swine fever (ASF) is a widespread hemorrhagic and highly contagious infectious disease caused by African swine fever virus (ASFV), currently threatening the pig industry worldwide. Here, we demonstrated that the cell-adapted strain ASFV-P121 with
Rui Luo, Tao Wang, Maowen Sun, Li Pan, Shujian Huang, Yun Sun, Hua-Ji Qiu   +6 more
doaj   +1 more source

Experimental pig-to-pig transmission dynamics for African swine fever virus, Georgia 2007/1 strain [PDF]

, 2015
African swine fever virus (ASFV) continues to cause outbreaks in domestic pigs and wild boar in Eastern European countries. To gain insights into its transmission dynamics, we estimated the pig-to-pig basic reproduction number (R 0) for the Georgia 2007 ...
Burnham, C. GUINAT, D. U. PFEIFFER, Diekmann, J. L. GONZALES, Keeling, L. DIXON, McVicar, S. GUBBINS, T. VERGNE, Vynnycky   +10 more
core   +2 more sources

Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions [PDF]

, 2016
African swine fever (ASF) is a major threat to the pig industry in Europe. Since 2007, ASF outbreaks have been ongoing in the Caucasus, Eastern Europe and the Baltic countries, causing severe economic losses for many pig farmers and pork producers.
BALDACCHINO, BLOME, BOINAS, COSTARD, DAVIES, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DE CARVALHO FERREIRA, DIAZ, EC, EC, EC, EC, EC, EFSA, EU, FAO, FAO, GABRIEL, GALLARDO, GALLARDO, GALLARDO, GOGIN, GREIG, GREIG, GUINAT, GUINAT, GULENKIN, HAAS, HEUSCHELE, HOWEY, IGLESIAS, KAGIRA, LANGE, MANZANO-ROMÁN, MCKERCHER, MCVICAR, MEBUS, MEBUS, MELLOR, MONTGOMERY, OGANESYAN, OIE, PARKER, PHENGSAVANH, PIETSCHMANN, PLOWRIGHT, PLOWRIGHT, PLOWRIGHT, ROWLANDS, SANCHEZ BOTIJA, SANCHEZ BOTIJA, SODEIKAT, THOMSON, THURFJELL, TURNER, VERGNE, VERGNE, VLASOVA, WILKINSON   +60 more
core   +2 more sources

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP

Viruses, 2020
African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs with significant economic consequences to the swine industry.
Elizabeth Ramírez-Medina, Elizabeth A. Vuono, Lauro Velazquez-Salinas, Ediane Silva, Ayushi Rai, Sarah Pruitt, Keith A. Berggren, James Zhu, Manuel V. Borca, Douglas P. Gladue   +9 more
doaj   +1 more source

Cellular immunity in ASFV responses

Virus Research, 2013
African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease with a mortality rate approaching 100% in domestic pigs. However, pigs can survive infection with less-virulent isolates of ASFV and may become chronically infected.
Haru-Hisa, Takamatsu, Michael S, Denyer, Anna, Lacasta, Catrina M A, Stirling, Jordi M, Argilaguet, Christopher L, Netherton, Chris A L, Oura, Carlos, Martins, Fernando, Rodríguez   +8 more
openaire   +2 more sources

Inoculation with ASFV-Katanga-350 Partially Protects Pigs from Death during Subsequent Infection with Heterologous Type ASFV-Stavropol 01/08

Viruses, 2023
African swine fever virus (ASFV) is an extremely genetically and phenotypically heterogeneous pathogen. Previously, we have demonstrated that experimental inoculation of pigs with an attenuated strain, Katanga-350 (genotype I, seroimmunotype I) (ASFV-Katanga-350), can induce protective immunity in 80% of European domestic pigs against the homologous ...
Mikhail E. Vlasov, Irina P. Sindryakova, Dmitry A. Kudrjashov, Sergey Y. Morgunov, Olga L. Kolbasova, Valentina M. Lyska, Sergey P. Zhivoderov, Elena Y. Pivova, Vladimir M. Balyshev, Alexey D. Sereda, Denis V. Kolbasov   +10 more
openaire   +3 more sources

Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis

Virology Journal, 2023
Background African swine fever virus (ASFV) is one of the most fatal swine etiological agents and has a huge economic impact on the global pork industry. Given that no effective vaccines or anti-ASFV drugs are available, there remains a pressing need for
Yang Chen, Yanchen Guo, Hao Chang, Zebu Song, Zhi Wei, Zhao Huang, Zezhong Zheng, Guihong Zhang, Yankuo Sun   +8 more
doaj   +1 more source