Results 41 to 50 of about 10,002 (242)

Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]

, 2010
Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A., EPIZONE (Funder), Fooks, A.R., Gale, P., Kelly, L., Kosmider, R., Ramnial, V., Snary, E.L.   +7 more
core   +1 more source

Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase [PDF]

BioImpacts
Introduction: African swine fever (ASF) continues to be a significant threat to the global livestock industry due to its severe impact on pig populations. Currently, there are no approved therapeutic agents for the virus, and biosecurity measures such as
Mark Andrian B. Macalalad, Fredmoore L. Orosco   +1 more
doaj   +1 more source

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine

Viruses, 2020
African swine fever virus (ASFV) is currently causing devastating outbreaks in Asia and Europe, and the ASFV strain Georgia (ASFV-G) is responsible for these outbreaks.
Elizabeth Ramirez-Medina, Elizabeth Vuono, Sarah Pruitt, Ayushi Rai, Ediane Silva, James Zhu, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever

Viruses, 2021
The African swine fever virus (ASFV) is currently causing a pandemic affecting wild and domestic swine from Western Europe to Asia. No commercial vaccines are available to prevent African swine fever (ASF), resulting in overwhelming economic losses to ...
Manuel V. Borca, Elizabeth Ramirez-Medina, Ediane Silva, Elizabeth Vuono, Ayushi Rai, Sarah Pruitt, Nallely Espinoza, Lauro Velazquez-Salinas, Cyril G. Gay, Douglas P. Gladue   +9 more
doaj   +1 more source

Dynamics of African swine fever virus shedding and excretion in domestic pigs infected by intramuscular inoculation and contact transmission [PDF]

, 2014
African swine fever virus (ASFV) is a highly virulent swine pathogen that has spread across Eastern Europe since 2007 and for which there is no effective vaccine or treatment available.
Dixon, L, Goatley, L, Guinat, C, Netherton, C L, Pfeiffer, D U, Pirbright, Reis, A L   +6 more
core   +5 more sources

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine

Viruses, 2023
African swine fever virus (ASFV) is the etiological agent of an economically important disease of swine currently affecting large areas of Africa, Eurasia and the Caribbean.
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ayushi Rai, Nallely Espinoza, Alyssa Valladares, Edward Spinard, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

A blocking ELISA based on virus-like nanoparticles chimerized with an antigenic epitope of ASFV P54 for detecting ASFV antibodies

Scientific Reports, 2023
AbstractAfrican swine fever virus (ASFV) is a highly lethal pathogen of domestic and wild pigs. Due to no vaccines or drugs available, early accurate diagnosis and eradication of infected animals are the most important measures for ASFV prevention and control.
Chaohua Huang, Chenfu Cao, Zhichao Xu, Yanxing Lin, Jiang Wu, Qiaoyu Weng, Zheng Liu, Ye Jin, Peng Chen, Qunyi Hua   +9 more
openaire   +3 more sources

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

Viruses, 2021
African swine fever virus (ASFV) causes a devastating disease of swine that has caused outbreaks in Central Europe since 2007, spreading into Asia in 2018.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source

The attenuated ASFV strains MK-200 and FK-32/135 as possible models for investigation of protective immunity by ASFV infection

PLOS ONE, 2022
African swine fever (ASF) is an infectious disease of domestic and wild pigs of all breeds and ages, with the acute form of the disease being characterized by high fever, hemorrhages in the reticuloendothelial system and a high mortality rate. Registered safe and efficacious ASF vaccines are not available.
Alexey D. Sereda, Anna S. Kazakova, Sanzhi G. Namsrayn, Mikhail E. Vlasov, Denis V. Kolbasov   +4 more
openaire   +3 more sources

Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro

Veterinary Research, 2023
African swine fever (ASF), caused by ASF virus (ASFV) infection, poses a huge threat to the pork industry owing to ineffective preventive and control measures. Hence, there is an urgent need to develop strategies, including antiviral drugs targeting ASFV,
Yang Chen, Zebu Song, Hao Chang, Yanchen Guo, Zhi Wei, Yankuo Sun, Lang Gong, Zezhong Zheng, Guihong Zhang   +8 more
doaj   +1 more source