Results 111 to 120 of about 2,024 (149)
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A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II
Naunyn-Schmiedeberg's Archives of Pharmacology, 1974Two new synthetic analogs of Asp1-Ile5-angiotensin II, Sar1-Ile5-Ile8-angiotensin II and (N,N-dimethyl) Gly1-Ile5-Ile8-angiotensin II which are chemically related, have a potent competitive antagonistic action against Asp1-β-amid-Val5-angiotensin II on the rabbit isolated aorta, rat ascending colon, isolated perfused heart of cat and in vivo on the ...
R K Türker +2 more
exaly +3 more sources
Tetrapod-Type [Asp1] Angiotensin Is Present in a Holostean Fish,Amia calva
General and Comparative Endocrinology, 1998The renin-angiotensin system has been identified in various vertebrates, from elasmobranchs to mammals. Tetrapod (amphibians to mammals) angiotensin (ANG) has Asp at the N-terminus, but Asp is replaced by Asn in elasmobranch and teleost fish. ANG I has been isolated from incubates of plasma and kidney extracts of the bowfin Amia calva, a holostean fish,
Y, Takei +4 more
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Biological activity of des-(Asp1, Arg2, Val3)-angiotensin II in man
Life Sciences, 1983Abstract When des-(Asp 1 , Arg 2 , Val 3 )-angiotensin II was infused iv at rates of 308–5,550 pmol/kg·min for 10–120 min into 5 normal men and 2 patients with Bartter's syndrome, no significant change was observed in blood pressure (BP), plasma renin activity (PRA) or plasma aldosterone (PA), and the lowest dose did not inhibit a captopril-induced ...
T, Kono +6 more
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The ASP1 gene of Saccharomyces cerevisiae, encoding the intracellular isozyme of l-asparaginase
Gene, 1994Saccharomyces cerevisiae produces two L-asparaginases (ASPs), intracellular ASP I and cell-wall ASP II. In this report, the ASP-I-encoding gene, ASP1, has been identified by homology cloning based on the structures of ASPs from other organisms. Its deduced protein product has a subunit M(r) of 41,414, and shows substantial sequence homology to the ...
K, Sinclair, J P, Warner, D T, Bonthron
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Clinical Science, 1978
1. Immunoreactive angiotensin II was measured in cerebrospinal fluid of four normal dogs. 2. The migration of this immunoreactive angiotensin II on polyacrylamide-slab gel electrophoresis was identical with the migration of the heptapeptide, Des-Asp1-angiotensin II, in each case. 3.
J S, Hutchinsón +3 more
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1. Immunoreactive angiotensin II was measured in cerebrospinal fluid of four normal dogs. 2. The migration of this immunoreactive angiotensin II on polyacrylamide-slab gel electrophoresis was identical with the migration of the heptapeptide, Des-Asp1-angiotensin II, in each case. 3.
J S, Hutchinsón +3 more
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INHIBITION OF ANGIOTENSIN III ACTION BY DES-ASP1-,ILEU8-ANGIOTENSIN II IN MAN
Acta Endocrinologica, 1978ABSTRACT In 5 normal men intravenous infusion of 600 ng/kg/min of des-asp1-,ileu8-angiotensin II (AIIIA) inhibited a rise in blood pressure as well as increase in plasma aldosterone caused by an intravenous infusion of 20 or 100 ng/kg/min of des-asp1-angiotensin II (angiotensin III, AIII). This result and our previous study on simultaneous infusions of
T, Kono +5 more
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Identification and Characterization of Schizosaccharomyces pombe asp1+, a Gene That Interacts with Mutations in the Arp2/3 Complex and Actin [PDF]
Genetics, 1999 Abstract The Arp2/3 complex is an essential component of the actin cytoskeleton in yeast and is required for the movement of actin patches. In an attempt to identify proteins that interact with this complex in the fission yeast Schizosaccharomyces pombe, we sought high-copy suppressors of the S.
Anna Feoktistova +2 more
exaly +3 more sources
Formation of angiotensin III from [des-Asp1]angiotensin I in the mesentric vasculature
American Journal of Physiology-Heart and Circulatory Physiology, 1979The effects of [des-Asp1]angiotensin I and angiotensin III on mesenteric blood flow were compared in 15 pentobarbital-anesthetized dogs. These agonists were administered as bolus injections directly into the vasculature supplied by the superior mesenteric artery.
J M, Sexton +4 more
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Evidence for the Existence of des-Asp1-Angiotensin II in Human Uterine and Adrenal Tissues*
The Journal of Clinical Endocrinology & Metabolism, 1985Renin is present in various tissues outside the kidney. In contrast, the levels of angiotensins (ANG), the active products of the renin-angiotensin system, have not been thoroughly evaluated in tissues. In this study, we demonstrated the presence of immunoreactive (ir) ANG I and ANG II in various human tissues by RIA.
MITSUHIDE NARUSE +10 more
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Evidence that des-Asp1 angiotensin II mediates the renin-angiotensin response.
Circulation Research, 1976Studies were undertaken to compare and evaluate the influence of angiotensin II and its heptapeptide fragments, des-Asp-1-angiotensin II, at various receptor sites for angiotensin in both dogs and rats. Receptor sites evaluated were those which are found in the glomerulosa, reticularis, and fasiculata of the adrenal cortex, in the renal arterioles and ...
R H, Freeman +3 more
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