Results 141 to 150 of about 7,135 (185)

Transcriptional corepressors in maize maintain meristem development. [PDF]

Plant Physiol
Gregory J, Liu X, Chen Z, Gallardo C, Punskovsky J, Koslow G, Galli M, Gallavotti A.   +7 more
europepmc   +1 more source

The Schizosaccharomyces pombe bifunctional enzyme Asp1 regulates cellular levels of 1,5-bisdiphosphoinositol tetrakisphosphate

, 2018
openaire   +1 more source

Structural basis for recognition of the FLAG-tag by anti-FLAG M2

Beugelink JW, Sweep E, Janssen BJ, Snijder J, Pronker MF.   +4 more
europepmc   +1 more source

Transcriptional Corepressor ASP1 and CLV-Like Signaling Regulate Meristem Maintenance in Rice [PDF]

Plant Physiology, 2019
Stem cell homeostasis is maintained by the WUSCHEL-CLAVATA (WUS-CLV) negative feedback loop in Arabidopsis (Arabidopsis thaliana). In rice (Oryza sativa), FLORAL ORGAN NUMBER2 (FON2) functions in the negative regulation of stem cell proliferation, similar to Arabidopsis CLV3 In this study, through genetic enhancer analysis, we found that loss of ...
Chie Suzuki, Wakana Tanaka, Hiro-Yuki Hirano   +2 more
exaly   +3 more sources

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Synthesis and evaluation of [des-Asp1]angiotensin I as a precursor for [des-Asp1]angiotensin II (angiotensin III)

Journal of Medicinal Chemistry, 1975
The nonapeptide [des-Asp1]angiotensin I (IV), synthesized by Merrifield's solid-phase procedure, was tested as a possible substrate for the converting enzymes from porcine lung and plasma. IV, [des-Asp1]angiotensin II (III), [des-(Asp1,Arg2)]angiotensin II (V), [des-(Asp1,Arg2,Val3)]angiotensin II (VI), [Sar1,Ile8]angiotensin II (VII), and [des-Asp1 ...
B S, Tsai, M J, Peach, M C, Khosla, F M, Bumpus   +3 more
openaire   +2 more sources

ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

Molecular and Cellular Neurosciences, 2000
Sequential proteolytic processing of the Amyloid Precursor Protein (APP) by beta- and gamma-secretases generates the 4-kDa amyloid (A beta) peptide, a key component of the amyloid plaques seen in Alzheimer's disease (AD). We and others have recently reported the identification and characterisation of an aspartic proteinase, Asp2 (BACE), as beta ...
I, Hussain, D J, Powell, D R, Howlett, G A, Chapman, L, Gilmour, P R, Murdock, D G, Tew, T D, Meek, C, Chapman, K, Schneider, S J, Ratcliffe, D, Tattersall, T T, Testa, C, Southan, D M, Ryan, D L, Simmons, F S, Walsh, C, Dingwall, G, Christie   +18 more
exaly   +3 more sources

Biological activity of des-(Asp1, Arg2, Val3)-angiotensin II in man

Life Sciences, 1983
Abstract When des-(Asp 1 , Arg 2 , Val 3 )-angiotensin II was infused iv at rates of 308–5,550 pmol/kg·min for 10–120 min into 5 normal men and 2 patients with Bartter's syndrome, no significant change was observed in blood pressure (BP), plasma renin activity (PRA) or plasma aldosterone (PA), and the lowest dose did not inhibit a captopril-induced ...
T, Kono, F, Oseko, F, Ikeda, R, Nakano, A, Taniguchi, H, Imura, M C, Khosla   +6 more
openaire   +2 more sources

INHIBITION OF ANGIOTENSIN III ACTION BY DES-ASP1-,ILEU8-ANGIOTENSIN II IN MAN

Acta Endocrinologica, 1978
ABSTRACT In 5 normal men intravenous infusion of 600 ng/kg/min of des-asp1-,ileu8-angiotensin II (AIIIA) inhibited a rise in blood pressure as well as increase in plasma aldosterone caused by an intravenous infusion of 20 or 100 ng/kg/min of des-asp1-angiotensin II (angiotensin III, AIII). This result and our previous study on simultaneous infusions of
T, Kono, F, Ikeda, F, Oseko, M, Nanno, H, Imura, J, Endo   +5 more
openaire   +4 more sources

Tetrapod-Type [Asp1] Angiotensin Is Present in a Holostean Fish,Amia calva

General and Comparative Endocrinology, 1998
The renin-angiotensin system has been identified in various vertebrates, from elasmobranchs to mammals. Tetrapod (amphibians to mammals) angiotensin (ANG) has Asp at the N-terminus, but Asp is replaced by Asn in elasmobranch and teleost fish. ANG I has been isolated from incubates of plasma and kidney extracts of the bowfin Amia calva, a holostean fish,
Y, Takei, Y, Itahara, D G, Butler, T X, Watanabe, G Y, Oudit   +4 more
openaire   +2 more sources