Results 21 to 30 of about 499,523 (302)
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]
, 1989 1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
J. J. Hablitz +3 more
core +2 more sources
The roles of organic acids in C4 photosynthesis
Frontiers in Plant Science, 2016 Organic acids are involved in numerous metabolic pathways in all plants. The finding that some plants, known as C4 plants, have four-carbon dicarboxylic acids as the first product of carbon fixation showed these organic acids play essential roles as ...
Martha eLudwig
doaj +1 more source
Plants, 2022 Aspartate is the most critical amino acid in the aspartate metabolic pathway, which is associated with multiple metabolic pathways, such as protein synthesis, nucleotide metabolism, TCA cycle, glycolysis, and hormone biosynthesis. Aspartate also plays an
Shuhan Lei +2 more
doaj +1 more source
Enzyme Nanosheet-Based Electrochemical Aspartate Biosensor for Fish Point-of-Care Applications
Micromachines, 2022 Bacterial infections in marine fishes are linked to mass mortality issues; hence, rapid detection of an infection can contribute to achieving a faster diagnosis using point-of-care testing.
Thenmozhi Rajarathinam +8 more
doaj +1 more source
Frontiers in Immunology, 2023 IntroductionMetabolic reprogramming potentiates host protection against antibiotic-sensitive or -resistant bacteria. However, it remains unclear whether a single reprogramming metabolite is effective enough to combat both antibiotic-sensitive and ...
Jiao Xiang +5 more
doaj +1 more source
eLife, 2020 Previously, we found that in glucose-limited Saccharomyces cerevisiae colonies, metabolic constraints drive cells into groups exhibiting gluconeogenic or glycolytic states.
Sriram Varahan +4 more
doaj +1 more source
Biomolecules, 2021 A better understanding of the metabolic constraints of a tumor may lead to more effective anticancer treatments. Evidence has emerged in recent years shedding light on a crucial aspartate dependency of many tumor types.
Iiro Taneli Helenius +2 more
doaj +1 more source
Chloroquine Triggers Cell Death and Inhibits PARPs in Cell Models of Aggressive Hepatoblastoma
Frontiers in Oncology, 2020 Background: Hepatoblastoma (HB) is the most common pediatric liver malignancy. Despite advances in chemotherapeutic regimens and surgical techniques, the survival of patients with advanced HB remains poor, underscoring the need for new therapeutic ...
Katja Eloranta +11 more
doaj +1 more source
Determination of aspartate kinase in maize tissues. [PDF]
, 2005 Lysine, threonine, methionine and isoleucine are synthesized from aspartate in a branched pathway in higher plants. Aspartate kinase plays a key role in the control of the aspartate pathway.
Ferreira, Renato Rodrigues +4 more
core +5 more sources
The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes [PDF]
, 2009 Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal
Attwell, D. +9 more
core +1 more source