Results 21 to 30 of about 467,415 (311)

Studying the Excitotoxic Amino Acids Impact on the Degree of Impairment of Consciousness in Purulent Meningitises in Children

Zdorovʹe Rebenka, 2013
The study revealed a strong and significant inverse correlation between the level of excitatory neurotransmitter amino acid of glutamate, aspartate in the blood serum and level of consciousness according to Glasgow Coma Scale.
L.V. Pypa, Т.V. Svistilnik
doaj   +1 more source

Acute severe hepatotoxicity associated with clomipramine

Psychiatry and Clinical Psychopharmacology, 2021
Miss Y. presented with complaints of irritability, depressed mood, avolition, anhedonia, markedly decreased appetite and around 10 kg weight loss within two months, amenorrhea, dysmorphophobia, and psychomotor retardation.
Murad Atmaca
doaj   +1 more source

Is Aspartate an Excitatory Neurotransmitter? [PDF]

, 2015
Recent evidence has resurrected the idea that the amino acid aspartate, a selective NMDA receptor agonist, is a neurotransmitter. Using a mouse that lacks the glutamate-selective vesicular transporter VGLUT1, we find that glutamate alone fully accounts ...
Edwards, Robert H, Nicoll, Roger A, Silm, Katlin, Herring, Bruce E   +3 more
core   +1 more source

Antidepressant Effect of Shaded White Leaf Tea Containing High Levels of Caffeine and Amino Acids

Molecules, 2020
The young leaves of green tea become lighter in color than usual when protected from sunlight by a shading net for about two weeks while growing. These leaves are called “shaded white leaf tea” or SWLT.
Keiko Unno, Daisuke Furushima, Yuzuki Nomura, Hiroshi Yamada, Kazuaki Iguchi, Kyoko Taguchi, Toshikazu Suzuki, Makoto Ozeki, Yoriyuki Nakamura   +8 more
doaj   +1 more source

Relapse risk factors in anti-N-methyl-D-aspartate receptor encephalitis

, 2019
Aim: To identify factors that may predict and affect the risk of relapse in anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Method: This was a retrospective study of an Italian cohort of patients with paediatric (≤18y) onset anti-NMDAR ...
Papetti L., Freri E., Suppiej A., Nosadini M., Sartori S., Matricardi S., Falsaperla, R., Granata T., Valeriani M., Ragona F., Splendiani A, Italian working group on paediatric anti-N-methyl-D-Aspartate receptor encephalittis   +11 more
core   +1 more source

The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

, 2009
Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal
Attwell, D., Koodziejczyk, Karolina, Kolodziejczyk, K., Wade, A., Kradttir, Ragnhildur, Wade, Anna, Karadottir, R., Hamilton, Nicola B.; id_orcid, Attwell, David, Hamilton, N. B.   +9 more
core   +1 more source

Sitting Interruption Modalities during Prolonged Sitting Acutely Improve Postprandial Metabolome in a Crossover Pilot Trial among Postmenopausal Women

Metabolites
Older adults sit during most hours of the day; more than 30% are considered physically inactive. The accumulation of prolonged sitting time is an exercise-independent risk factor for aging-related conditions such as cardiometabolic disease and cancer ...
Jeffrey S. Patterson, Brinda K. Rana, Haiwei Gu, Dorothy D. Sears   +3 more
doaj   +1 more source

Bacterial aspartic proteinases [PDF]

FEBS Letters, 1997
Regions of genomic DNA encoding putative aspartic proteinase domains were amplified by PCR from the bacterial species, Escherichia coli and Haemophilus influenzae. Expression of each of these DNA fragments resulted in the accumulation of the corresponding recombinant proteins in insoluble aggregates.
Hill, Jeffrey, Phylip, Lowri H
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages

Frontiers in Immunology, 2021
Increasing evidence support that cellular amino acid metabolism shapes the fate of immune cells; however, whether aspartate metabolism dictates macrophage function is still enigmatic.
Hao Wang, Xueyue Zheng, Bingnan Liu, Yaoyao Xia, Zhongquan Xin, Baichuan Deng, Liuqin He, Liuqin He, Jinping Deng, Wenkai Ren   +9 more
doaj   +1 more source