Results 41 to 50 of about 467,415 (311)

Acylation of aspartate aminotransferase [PDF]

Biochemical Journal, 1967
1. Acetylation of aspartate aminotransferase from pig heart inhibits completely the enzymic activity when the coenzyme is in the amino form (pyridoxamine phosphate) or when the coenzyme has been removed, but not when the coenzyme is in the aldehyde form (pyridoxal phosphate). 2.
C, Turano, A, Giartosio, F, Riva, V, Baroncelli   +3 more
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

presentation_1_In Vivo Multimodal Magnetic Resonance Imaging Changes After N-Methyl-d-Aspartate-Triggered Spasms in Infant Rats.PDF

, 2018
ObjectiveDespite the serious neurodevelopmental sequelae of epileptic encephalopathy during infancy, the pathomechanisms involved remain unclear. To find potential biomarkers that can reflect the pathogenesis of epileptic encephalopathy, we explored the ...
Mi-Sun Yum (5104079), Minyoung Lee (484115), Woo-Hyun Shim (4608091), Tae-Sung Ko (5104082), Dong-Cheol Woo (3174477), Libor Velíšek (345515)   +5 more
core   +1 more source

Selective Plasmatic Amino Acid Alterations as a Potential Biomarker for Pathological Stratification in Autism Spectrum Disorders

Biomedicines
Background: Autism Spectrum Disorders (ASD) are neurodevelopmental disorders characterized by repetitive behaviors and social interaction deficits. While the severity of ASD is classified into levels (1–3) by the DSM-5, reliable circulating biomarkers to
Andrea De Giacomo, Nicoletta Lionetti, Maria Grazia Di Lago, Simonetta Simonetti, Giulia Iapadre, Alessandro Rizzello, Vittorio Sanginario, Federica Gradia, Donatella Tansella, Eustachio Vitullo, Marta Simone, Dario Sardella, Tania Lorè, Roberta Cardinali, Silvia Russo, Vincenzo Salpietro, Salvatore Scacco, Maurizio Delvecchio, Antonio Gnoni   +18 more
doaj   +1 more source

Uncoupling Protein 3 Catalyzes the Exchange of C4 Metabolites Similar to UCP2

Biomolecules, 2023
Uncoupling protein 3 (UCP3) belongs to the mitochondrial carrier protein superfamily SLC25 and is abundant in brown adipose tissue (BAT), the heart, and muscles.
Jürgen Kreiter, Tatyana Tyschuk, Elena E. Pohl   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

presentation_2_In Vivo Multimodal Magnetic Resonance Imaging Changes After N-Methyl-d-Aspartate-Triggered Spasms in Infant Rats.ppt

, 2018
ObjectiveDespite the serious neurodevelopmental sequelae of epileptic encephalopathy during infancy, the pathomechanisms involved remain unclear. To find potential biomarkers that can reflect the pathogenesis of epileptic encephalopathy, we explored the ...
Mi-Sun Yum (5104079), Minyoung Lee (484115), Woo-Hyun Shim (4608091), Tae-Sung Ko (5104082), Dong-Cheol Woo (3174477), Libor Velíšek (345515)   +5 more
core   +1 more source

Regulación de la utilización del aspartato por los astrocitos durante la prelactancia

Universitas Scientiarum, 2009
Regulation of the use of aspartate by the astrocytes during the presuckling period. During the perinatal period the concentration ofN-acetyl-L-aspartate (NAA) produced by neurons increases.
Cecilia Espíndola, Ludis Morales, María Juliana Salamanca Ortiz, Jairo Alfonso Tovar-Franco   +3 more
doaj  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Determination of aspartate kinase in maize tissues. [PDF]

, 2005
Lysine, threonine, methionine and isoleucine are synthesized from aspartate in a branched pathway in higher plants. Aspartate kinase plays a key role in the control of the aspartate pathway.
Ferreira, Renato Rodrigues, Gratão, Priscila Lupino, Lea,Peter John, Azevedo, Ricardo Antunes, Gratão,Priscila Lupino, Vendemiatti,Ariane, Azevedo,Ricardo Antunes, Lea, Peter John, Ferreira,Renato Rodrigues, Lea, Peter J., Vendemiatti, Ariane   +10 more
core   +1 more source