Results 31 to 40 of about 499,523 (302)

Human D-aspartate Oxidase: A Key Player in D-aspartate Metabolism [PDF]

open access: yes, 2021
In recent years, the D-enantiomers of amino acids have been recognized as natural molecules present in all kingdoms, playing a variety of biological roles.
Giulia Murtas   +7 more
core   +1 more source

Studying the Excitotoxic Amino Acids Impact on the Degree of Impairment of Consciousness in Purulent Meningitises in Children

open access: yesZdorovʹe Rebenka, 2013
The study revealed a strong and significant inverse correlation between the level of excitatory neurotransmitter amino acid of glutamate, aspartate in the blood serum and level of consciousness according to Glasgow Coma Scale.
L.V. Pypa, Т.V. Svistilnik
doaj   +1 more source

Acute severe hepatotoxicity associated with clomipramine

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Miss Y. presented with complaints of irritability, depressed mood, avolition, anhedonia, markedly decreased appetite and around 10 kg weight loss within two months, amenorrhea, dysmorphophobia, and psychomotor retardation.
Murad Atmaca
doaj   +1 more source

Bacterial aspartic proteinases [PDF]

open access: yesFEBS Letters, 1997
Regions of genomic DNA encoding putative aspartic proteinase domains were amplified by PCR from the bacterial species, Escherichia coli and Haemophilus influenzae. Expression of each of these DNA fragments resulted in the accumulation of the corresponding recombinant proteins in insoluble aggregates.
Hill, Jeffrey, Phylip, Lowri H
openaire   +2 more sources

Antidepressant Effect of Shaded White Leaf Tea Containing High Levels of Caffeine and Amino Acids

open access: yesMolecules, 2020
The young leaves of green tea become lighter in color than usual when protected from sunlight by a shading net for about two weeks while growing. These leaves are called “shaded white leaf tea” or SWLT.
Keiko Unno   +8 more
doaj   +1 more source

Sitting Interruption Modalities during Prolonged Sitting Acutely Improve Postprandial Metabolome in a Crossover Pilot Trial among Postmenopausal Women

open access: yesMetabolites
Older adults sit during most hours of the day; more than 30% are considered physically inactive. The accumulation of prolonged sitting time is an exercise-independent risk factor for aging-related conditions such as cardiometabolic disease and cancer ...
Jeffrey S. Patterson   +3 more
doaj   +1 more source

Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages

open access: yesFrontiers in Immunology, 2021
Increasing evidence support that cellular amino acid metabolism shapes the fate of immune cells; however, whether aspartate metabolism dictates macrophage function is still enigmatic.
Hao Wang   +9 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Role of Aspartate in Immune Response and Mortality in a Polymicrobial Sepsis Model: Insights from Metabolomics and Transcriptomics

open access: yesCells
Sepsis is a life-threatening syndrome characterized by dysregulated host responses to infection. In addition to early hyperinflammation, many patients develop profound immune suppression, and multiple targeted immunotherapies have failed to improve ...
Min Ji Lee   +19 more
doaj   +1 more source

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