Results 71 to 80 of about 467,415 (311)
Maintaining cytosolic aspartate levels is a major function of the TCA cycle in proliferating cells
Molecular & Cellular Oncology, 2019 Cancer cells rely on glutamine to fuel mitochondria, however it remains unclear whether this is needed for bioenergetic or biosynthetic pathways. Our study suggests that an essential function of mitochondrial glutamine metabolism is to provide aspartate ...
H. Furkan Alkan +1 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe,
Minseong Chae +27 more
wiley +1 more source
Mitochondrial Regulation of the 26S Proteasome
Cell Reports, 2020 Summary: The proteasome is the main proteolytic system for targeted protein degradation in the cell and is fine-tuned according to cellular needs.
Thomas Meul +23 more
doaj +1 more source
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source
, 1982 C6HxsN40 +.C4H6NO~-, monoclinic, P2,,a = 5.511 (3), b = 8.438 (4), c = 15.265 (9) A, fl = 97.9 (I) °, D,, -- 1.467 (8) (flotation), D c = 1.452 Mg m -a, Z = 2.
Salunke, DM, Vijayan, M
core +2 more sources
Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH
Cell Reports, 2016 Although aberrant metabolism in tumors has been well described, the identification of cancer subsets with particular metabolic vulnerabilities has remained challenging.
Eric L. Allen +17 more
doaj +1 more source
Advanced Materials, EarlyView.A fully flexible ion‐gel‐gated graphene‐channel transistor driven by a triboelectric nanogenerator enables self‐powered tactile sensing and synaptic learning. Mimicking spike‐rate‐dependent plasticity, the device exhibits frequency‐selective potentiation and depression, supporting rate‐coded neuromorphic computation even under flex.
Hanseong Cho +3 more
wiley +1 more source
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
, 1999 L-Aspartate oxidase is a flavoprotein catalyzing the first step in the de novo biosynthesis of pyridine nucleotides in E. coli. Binding of FAD to L- aspartate oxidase is relatively weak (K(d) 6.7 x 10-7 M), resulting in partial loss of the coenzyme under
C. Treu +13 more
core +1 more source
Advanced Materials, EarlyView.SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung +6 more
wiley +1 more source