Aspartic Acid in Health and Disease. [PDF]
Nutrients, 2023 Aspartic acid exists in L- and D-isoforms (L-Asp and D-Asp). Most L-Asp is synthesized by mitochondrial aspartate aminotransferase from oxaloacetate and glutamate acquired by glutamine deamidation, particularly in the liver and tumor cells, and ...
Holeček M.
europepmc +4 more sources
Sweet Dreams (Are Made of This): A Review and Perspectives on Aspartic Acid Production
Fermentation, 2021 Aspartic acid, or “aspartate,” is a non-essential, four carbon amino acid produced and used by the body in two enantiomeric forms: L-aspartic acid and D-aspartic acid.
Holly Appleton, Kurt A. Rosentrater
doaj +2 more sources
Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma [PDF]
Laryngoscope Investigative Otolaryngology, 2022 Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya +12 more
doaj +2 more sources
Sarcopenia and aspartic acid magnesium
Journal of Physical Fitness and Sports Medicine, 2015 Sarcopenia from aging, inactivity, weightlessness, disease and malnutrition causes social problems due to associated physical dysfunction, a decrease in QOL, and risk of death.
Shigeru Yamada +4 more
doaj +4 more sources
Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect: a multistage metabolomic profiling and Mendelian randomization study [PDF]
Cancer Biology & MedicineObjective: Based on multistage metabolomic profiling and Mendelian randomization analyses, the current study identified plasma metabolites that predicted the risk of developing gastric cancer (GC) and determined whether key metabolite levels modified the
Mengyuan Wang +10 more
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Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction [PDF]
mAbs, 2023 In this study, we report the isomerization of an aspartic acid residue in the complementarity-determining region (CDR) of crizanlizumab as a major degradation pathway.
Fabian Bickel +15 more
doaj +2 more sources
Sensitive and Rapid Detection of Aspartic Acid with Co3O4-ZnO Nanorods Using Differential Pulse Voltammetry [PDF]
Biosensors, 2023 Herein, the detection of aspartic acid by doped Co3O4-ZnO nanorod materials was proposed using differential pulse voltammetry. The nano-composite metal oxide was synthesized by the wet precipitation method in basic media. Aspartic acid is a non-essential
Sulaiman Y. Alfaifi +3 more
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Building the uracil skeleton in primitive ponds at the origins of life: carbamoylation of aspartic acid [PDF]
Scientific Reports, 2022 A large set of nucleobases and amino acids is found in meteorites, implying that several chemical reservoirs are present in the solar system. The “geochemical continuity” hypothesis explores how protometabolic paths developed from so-called “bricks” in ...
Louis M. P. Ter-Ovanessian +2 more
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BIOTIN AND THE SYNTHESIS OF ASPARTIC ACID BY MICROORGANISMS [PDF]
Journal of Biological Chemistry, 1947 J. L. Stokes +2 more
openalex +6 more sources
Amino acids foliar application for maximizing growth, productivity and quality of peanut grown under sandy soil [PDF]
Brazilian Journal of Biology, 2023 Two field experiments were conducted during 2019 and 2020 summer seasons at the experimental station of national research center, Al-Nubaryia district, El-Behaira Governorate, Egypt, to study the effect of Phenyl alanine and Aspartic acid foliar ...
M. S. Sadak +3 more
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