Results 91 to 100 of about 5,130,397 (333)
Detecting Electron Transport of Amino Acids by Using Conductance Measurement
Sensors, 2017 The single molecular conductance of amino acids was measured by a scanning tunneling microscope (STM) break junction. Conductance measurement of alanine gives out two conductance values at 10−1.85 G0 (1095 nS) and 10−3.7 G0 (15.5 nS), while similar ...
Wei-Qiong Li +8 more
doaj +1 more source
Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells
Advanced Science, EarlyView.Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng +14 more
wiley +1 more source
Advanced Science, EarlyView.Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li +14 more
wiley +1 more source
Life, 2016 We have previously proposed that tRNAGly was the first tRNA and glycine was the first amino acid incorporated into the genetic code. The next two amino acids incorporated would have been the other two small hydrophilic amino acids serine and aspartic ...
Harold S. Bernhardt
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Advanced Science, EarlyView.KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma +9 more
wiley +1 more source
A Colorimetric Procedure for the Determination of Aspartic Acid.
Experimental Biology and Medicine, 1950 SummaryA procedure is described for the determination of aspartic acid in quantities of 0.5 mg or above in the sample. The amino acid is converted to fumaric acid and this is measured colorimetrically.
Lawrence M. Marshall, Felix Friedberg
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Advanced Science, EarlyView.This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen +9 more
wiley +1 more source
Studies in Plant Metabolism. VI. Effect of 2,4-D on the Metabolism of Aspartic Acid and Glutamic Acid in the Bean Plant. [PDF]
, 1956 Thomas Jefferson Akers, S. C. Fang
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THE SYNTHESIS OF ASPARTIC ACID [PDF]
Journal of Biological Chemistry, 1933 Sidney W. Fox, Max S. Dunn
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RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics
Advanced Science, EarlyView.RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu +19 more
wiley +1 more source