Results 131 to 140 of about 5,196,013 (375)

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

Regulation of glycolipid and amino acid metabolism in juvenile triploid crucian carp (Carassius auratus) by oral administration of aspartic acid

Aquaculture Reports
Aspartic acid, a nonessential amino acid, plays crucial roles in protein synthesis, tricarboxylic acid cycle, and glycolipid metabolism in mammals. However, corresponding studies of the role of aspartic acid in fish remain limited.
Yu Wang, Bo Dong, Liyun Wu, Dong Han, Xiaoming Zhu, Haokun Liu, Yunxia Yang, Shouqi Xie, Zhen Liu, Junyan Jin   +9 more
doaj  

The C-terminus of Wheat streak mosaic virus Coat Protein Is Involved in Differential Infection of Wheat and Maize through Host-Specific Long-Distance Transport

Molecular Plant-Microbe Interactions, 2014
Viral determinants and mechanisms involved in extension of host range of monocot-infecting viruses are poorly understood. Viral coat proteins (CP) serve many functions in almost every aspect of the virus life cycle.
Satyanarayana Tatineni, Roy French
doaj   +1 more source

THE SYNTHESIS OF INDOLE-3-ACETYL-D,L-ASPARTIC ACID AND RELATED COMPOUNDS [PDF]

, 1956
Norman E. Good
openalex   +1 more source

Plasmonic‐Hydrogel Hybrid Biomaterials Via In Situ Seeded Growth

Angewandte Chemie, EarlyView.
Detailed chemical analysis of the interactions between Au3+ ions and gelatin‐based hydrogels enables the development of a robust “in situ” seed‐mediated synthesis of plasmonic gold nanoparticles, whereby gold salts are reduced directly on the surface of hydrogel substrates to form the nanostructures.
Gail A. Vinnacombe‐Willson, Manuel Núñez‐Martínez, Ada Herrero‐Ruiz, Francisco Bevilacqua, Raquel Pazos, Lara Troncoso‐Afonso, Marta Gallego‐González, Leonardo Scarabelli, Luis M. Liz‐Marzán   +8 more
wiley   +2 more sources

Enrichment of Non-Terrestrial L-Proteinogenic Amino Acids by Aqueous Alteration on the Tagish Lake Meteorite Parent Body [PDF]

The distribution and isotopic and enantiomeric compositions of amino acids found in three distinct fragments of the Tagish Lake C2-type carbonaceous chondrite were investigated via liquid chromatography fluorescence detection time-of-flight mass ...
Burton, Aaron S., Callahan, Michael P., Dworkin, Jason P., Elsila, Jamie E., Glavin, Daniel P., Herd, Christopher D. K.   +5 more
core   +1 more source

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

Advanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz, Dan Pascal Jean Albers, Fabian Zech, Julie Vandeput, Lieve Naesens, Giorgio Fois, Veronika Neubauer, Nico Preising, Emilia Schmierer, Yasser Almeida‐Hernandez, Moritz Petersen, Ludger Ständker, Sebastian Wiese, Peter Braubach, Manfred Frick, Eberhard Barth, Daniel Sauter, Frank Kirchhoff, Elsa Sanchez‐Garcia, Annelies Stevaert, Jan Münch   +24 more
wiley   +1 more source

Manometric determination of l-aspartic acid and l-asparagine [PDF]

, 1951

openalex   +1 more source

A Recent Progress on Upgrading of Furfural and Derivatives into Green Transport Fuels and Precursors via CC Coupling Reactions

Advanced Energy and Sustainability Research, EarlyView.
This review highlights recent advancements in converting lignocellulosic biomass to fuel precursors. It emphasizes the role of FUR and 2‐methylfuran in aldol condensation and hydroxyalkylation–alkylation reactions. The article discusses their efficiency, potential applications, and emerging technologies that promise cleaner and more sustainable energy ...
Errol D. Saluta, Mahlet N. Gebresillase, Jeong Gil Seo   +2 more
wiley   +1 more source

Antiparallel β‐Sheet as a Key Motif of Amyloid‐β Inhibitor Designed via Topological Peptide Reprogramming

Angewandte Chemie, EarlyView.
Targeting Amyloid‐β (Aβ) aggregation requires a peptide‐based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β‐sheets within the dimeric peptide.
Dongjoon Im, Ye Eun Lee, Gyusub Yoon, William A. Goddard III, Tae Su Choi, Hugh I. Kim   +5 more
wiley   +2 more sources