Results 131 to 140 of about 222,384 (349)

Integrin αvβ6‐Targeted PET/CT Imaging of Non‐Small Cell Lung Cancer with [68Ga]Ga‐Trivehexin: Improved Preoperative Lymph Node Staging and Association with Immunohistochemistry

open access: yesAdvanced Science, EarlyView.
Integrin αvβ6‐targeted [68Ga]Ga‐Trivehexin positron emission tomography/computed tomography (PET/CT) can accurately identify regional lymph nodes and cerebral metastases in non‐small cell lung cancer (NSCLC) compared with 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG).
Huiqin Wu   +9 more
wiley   +1 more source

Action of acids and alkalies on asparagin and aspartic acid [PDF]

open access: yesThe London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science
n ...
openaire   +2 more sources

A peptide fraction in liver [PDF]

open access: yes, 1949
We reported in a preliminary communication (1) the isolation of a peptide fraction from guinea pig liver. The following points of interest appeared at once: many different amino acids were obtained on hydrolysis; the peptide fraction contained most of ...
Borsook, Henry   +4 more
core  

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

open access: yesAdvanced Science, EarlyView.
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang   +7 more
wiley   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

open access: yesAdvanced Science, EarlyView.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li   +6 more
wiley   +1 more source

A quadratic multinomial regression model was established for taste properties of main catechins and amino acid monomers in green tea

open access: yesShipin yu jixie
ObjectiveTo study the flavor intensity of green tea after mixing the main flavor monomers.MethodsThree main catechins [epigallocatechin gallate (EGCG), epigallocatechin gallate (GCG), epicatechin gallate (ECG)] and three amino acid monomers (aspartic ...
RAN Qiansong   +5 more
doaj   +1 more source

Vortex‐Generated Microdroplets Enable Simple, Rapid, and Low‐Volume Measurement of Condensate Volume and Concentration

open access: yesAdvanced Science, EarlyView.
This work leverages vortex‐generated microdroplets to encapsulate condensates and quantify their volumes and concentrations. Compared to conventional bulk methods, the technique substantially reduces sample volume, cost, and processing time. Its broad utility sheds light on a wide range of applications, particularly those that require high‐throughput ...
Feipeng Chen, Ho Cheung Shum
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Multiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn’s disease

open access: yesEMBO Molecular Medicine
Intestinal fibrosis is the primary cause of disability in patients with Crohn’s disease (CD), yet effective therapeutic strategies are currently lacking.
Xuehua Li   +22 more
doaj   +1 more source

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