Results 41 to 50 of about 5,130,397 (333)

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

Advanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma, Om Shanker Tiwari, Vijay Kumar Patel, Ruchi Shukla, Ehud Gazit, Pandeeswar Makam   +5 more
wiley   +1 more source

Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. [PDF]

PLoS ONE, 2016
We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics.
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum   +10 more
doaj   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

A comparison between incremental lines of cementum and aspartic acid racemization in age estimation: histological and biochemical study

Egyptian Journal of Forensic Sciences, 2023
Background Age estimation is a vital aspect of the identification of an individual in forensic science. Teeth are one of the toughest structures in the human body and generally survive postmortem destruction.
Dena Mohamed Naguib Abdel Moawed, Nadia Mohsen Ali Ibrahim, Ibrahim Mohamed Eid, Amir Soliman, Heba El-Sayed Mostafa   +4 more
doaj   +1 more source

Redox- and pH-responsive cysteamine-modified poly(aspartic acid) showing a reversible sol-gel transition.

Macromolecular Bioscience, 2013
Synthesis and characterization of a pH- and redox-sensitive hydrogel of poly(aspartic acid) are reported. Reversible gelation and dissolution are achieved both in dimethylformamide and in aqueous medium via a thiol-disulphide interconversion in the side ...
B. Gyarmati, B. Vajna, Á. Némethy, K. László, A. Szilágyi   +4 more
semanticscholar   +1 more source

A Conformationally Restricted Aspartic Acid Analogue

Acta Crystallographica Section C Crystal Structure Communications, 1996
In the title compound, (1R,2R,3S,4S)-3-benzamido-3-methoxycarbonylbicyclo[2.2.1]heptane-2-carboxylic acid, C17H19NO5, the norbornyl group shows distortion from C2v(mm2) symmetry of the parent hydrocarbon. The values determined for the torsion angles about the N-C[alpha] ([varphi]) and C[alpha]-CO ([psi]) bonds correspond to a semi-extended conformation
Buñuel, Elena, Cativiela, Carlos, Díaz de Villegas, María D., Gálvez, José A.   +3 more
openaire   +3 more sources

Bioinspired Shape Reconfigurable, Printable, and Conductive “E‐Skin” Patch with Robust Antibacterial Properties for Human Health Sensing

Advanced Functional Materials, EarlyView.
In this article, Hojin Kim, Sayan Deb Dutta, and co‐workers report a shape‐reconfigurable, 3D printable, and highly adhesive slime‐like ‘electronic skin’ or ‘E‐skin’ patch for human health sensing and tissue engineering applications. The dual reinforcement of hydrogel patch with carbon nanotubes (CNTs) and cellulose nanocrystals (CNCs) improve the ...
Hojin Kim, Sayan Deb Dutta, Myoung Joon Jeon, Jieun Lee, Hyeonseo Park, Youjin Seol, Ki‐Taek Lim   +6 more
wiley   +1 more source

Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea

JCI Insight, 2022
Rosacea is a chronic skin disorder characterized by abnormal neurovascular and inflammatory conditions on the central face. Despite increasing evidence suggesting that rosacea is associated with metabolic disorders, the role of metabolism in rosacea ...
Tangxiele Liu, Wenqin Xiao, Mengting Chen, Rui Mao, Xu San, Qinqin Peng, Zhixiang Zhao, Qian Wang, Hongfu Xie, Zhili Deng, Ji Li   +10 more
doaj   +1 more source

Difference in chemotaxis of Salmonella cells between serine and aspartic acid

Journal of Biomechanical Science and Engineering, 2021
We investigated how the chemotactic behaviors of peritrichous bacteria that repeat straight swimming (runs) and directional changes (tumbles) differ depending on the chemical species and concentrations of the attractant.
Tonau NAKAI, Yasutoshi HIGASHIDA, Fumiya NAKAMURA, Tomonobu GOTO   +3 more
doaj   +1 more source