Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers. [PDF]
, 2018 Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2
Kato, Masato +5 more
core
Hybrid gold single crystals incorporating amino acids
, 2016 Composite hybrid gold crystals are of profound interest in various research areas ranging from materials science to biology. Their importance is due to their unique properties and potential implementation, for example in sensing or in bio-nanomedicine ...
Chen, Linfeng +4 more
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The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]
, 1991 The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard +3 more
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Aquaculture ReportsAspartic acid, a nonessential amino acid, plays crucial roles in protein synthesis, tricarboxylic acid cycle, and glycolipid metabolism in mammals. However, corresponding studies of the role of aspartic acid in fish remain limited.
Yu Wang +9 more
doaj +1 more source
Czech Journal of Food Sciences, 2006 This review article gives a survey of principal pathways that lead to the biosynthesis of the proteinogenic amino acids of the glutamic acid group (glutamic acid, glutamine, proline, arginine) and aspartic acid group (aspartic acid, asparagine, threonine,
Jan Velíšek, Karel Cejpek
doaj +1 more source
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data [PDF]
, 2008 Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughput protein identification using mass spectrometry (MS).
Bowler, Lucas D. +2 more
core +5 more sources
The effects of added salt on the second virial coefficients of the complete proteome of E. coli [PDF]
, 2002 Bacteria typically have a few thousand different proteins. The number of proteins with a given charge is a roughly Gaussian function of charge - centred near zero, and with a width around ten (in units of the charge on the proton).
Richard P. Sear, Runcong K.
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Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene [PDF]
, 2017 Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene.
Catchpole, B +5 more
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Amino acid racemization dating of marine shells: a mound of possibilities [PDF]
, 2007 Shell middens are one of the most important and widespread indicators for human exploitation of marine resources and occupation of coastal environments. Establishing an accurate and reliable chronology for these deposits has fundamental implications for ...
Bailey, Geoffrey N. +5 more
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Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. [PDF]
PLoS ONE, 2016 We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics.
Eric S Okerberg +10 more
doaj +1 more source