Results 51 to 60 of about 3,515,668 (311)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The Online Faculty Development and Assessment System [PDF]

, 2006
This article evaluates the role of the Online Faculty Development and Assessment System (OFDAS), created at universities in the Canary Islands, Spain, in staff development.
Alegre, Olga, Villar, Luis
core   +5 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Concepciones del profesorado de geografía e historia sobre la evaluación de los aprendizajes

Actualidades Investigativas en Educación, 2016
El presente artículo aborda la temática de la evaluación del aprendizaje a partir de las concepciones sobre dicho proceso que tiene el profesorado de Geografía e Historia de Educación Secundaria Obligatoria (ESO), en 31 centros educativos de la Región de
M. Begoña Alfageme González, José Monteagudo Fernández, Pedro Miralles Martínez   +2 more
doaj   +1 more source

The evolving link between learning and assessment : from 'transmission check' to 'learning support' [PDF]

, 2005
Learning and assessment are now considered as two sides of the same coin we simply cannot speak of one without also referring to the other. This paper, which traces the evolution of the link between learning and assessment, explores what led to our ...
Buhagiar, Michael A.
core  

Online peer assessment: helping to facilitate learning through participation [PDF]

, 2012
The focus of this paper is on the combination of enquiry-based learning, information literacy and e-learning and how they are embedded in an online peer assessment exercise.
Cleland, Jamie, Walton, Geoff
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Preface : CAA 2010: Computer assisted assessment: supporting student learning [PDF]

, 2011
The Preface for the first special issue for the International Journal of e-Assessment highlights the role of the assessment for learning agenda. It also points to papers within the special issue which relate to: (a) Overcoming the barriers to supporting
Warburton, Bill, Whitelock, Denise
core  

Assessment innovation and student experience: a new assessment challenge and call for a multi-perspective approach to assessment research [PDF]

, 2014
The impact of innovative assessment on student experience in higher education is a neglected research topic. This represents an important gap in the literature given debate around the marketization of higher education, international focus on student ...
Bazeley P., Biggs J., Boud D., Buckley A., Chalmers D., Clegg K., Department for Business Innovation and Skills, Department for Business Innovation and Skills, Falchikov N., Foskett N., Furedi F., Gibbs G., Gibbs G., Gov.UK, Higher Education Academy, Higher Education Academy, Hounsell D., Marton F., McDowell L., Oberg K., Race P., Sambell K., Sheena Bevitt, UK Homeoffice, UKCISA (UK Council for International Student Affairs), Welikala T., Williams J.   +26 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source