Results 121 to 130 of about 1,135 (159)

Astragaloside IV and Cycloastragenol Production Capacity of Astragalus trojanus Calli

open access: yes, 2015
Astragalus species are medicinal plants which produce valuable secondary metabolites, especially cycloartane-type glycosides. In this study, stem and leaf explants of Astragalus trojanus were subjected to different plant growth regulators, environmental conditions and media compositions to identify their callus responses.
Nartop, Pinar   +3 more
openaire   +2 more sources

Astragaloside IV alleviates heart failure by modulating Nrf-2

open access: yesChinese Medical Journal, 2021
Wenxiao Feng   +7 more
openaire   +3 more sources
Some of the next articles are maybe not open access.

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Research progress on the antitumor effects of astragaloside IV

European Journal of Pharmacology, 2023
One of the most important and effective components of Astragalus membranaceus is astragaloside IV (AS-IV), which can exert anti-tumor effects through various pathways. For instance, AS-IV exerts an anti-tumor effect by acting at the cellular level, regulating the phenotype switch of tumor-associated macrophages, or inhibiting the development of tumor ...
Ruixi Zhou
exaly   +3 more sources

Pharmacological effects of Astragaloside IV: a literature review

open access: yesJournal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan / Sponsored By All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine, 2013
To review the pharmacological effects and mechanisms of action of Astragaloside IV in Huangqi (Radix Astragali Mongolici).Aticles focusing on Astragaloside IV in English and Chinese in databases were collected and reviewed in order to summarize the latest extraction separation, pharmacokinetics, and the pharmacological effects of astrageloside IV ...
Yongping Mu, Mingyu Sun, Ping Liu
exaly   +3 more sources

The state of astragaloside IV research: A bibliometric and visualized analysis

Fundamental & Clinical Pharmacology, 2023
AbstractBackgroundAstragaloside IV has emerged as a pharmaceutical monomer with great medical applications and potential. Astragaloside IV has many effects such as improving myocardial ischemia, cerebral ischemia–reperfusion injury, anti‐inflammatory, analgesic, antiviral, promoting lymphocyte proliferation, and antitumor effects.
Ning Liu, Yansu Ji, Rui Liu, Xin Jin
openaire   +2 more sources

Microbial transformation of astragalosides to astragaloside IV by Absidia corymbifera AS2

Process Biochemistry, 2011
Abstract Astragaloside IV (ASI) is the main active constituent of astragalosides in Radix Astragali . Its content in natural plants is relatively low. We selected the strain Absidia corymbifera AS2 to transform astragalosides to ASI. This strain enhanced ASI production approximately fourfold when cultures were supplemented with 5 g/L of crude ...
Li Ye   +7 more
openaire   +1 more source

Antiviral activity of astragaloside II, astragaloside III and astragaloside IV compounds against dengue virus: Computational docking and in vitro studies

Microbial Pathogenesis, 2021
This study was aimed to identify the phytocompounds possessing anti-dengue virus activity using in silico and in vitro approaches. A total of 7000 phytocompounds were virtually screened against protein targets (envelope, NS2b/NS3, and NS5) of dengue virus using iGEMDOCK and individually docked using Maestro 10.7 module of Schrödinger software. In vitro
Purushothaman, Indu   +5 more
exaly   +3 more sources

Effects of astragaloside IV on the pharmacokinetics of puerarin in rats

Xenobiotica, 2019
Radix astragali and puerarin are always used together for cardiovascular disease in China clinics. This study investigates the effects of astragaloside IV (AS-IV, the main components of radix astragali) on the pharmacokinetics of puerarin in rats. The pharmacokinetics of orally administered puerarin (50 mg/kg) with or without AS-IV pretreatment (100 mg/
Lu, Liu   +3 more
openaire   +2 more sources

A novel biotransformation of astragalosides to astragaloside IV with the deacetylation of fungal endophyte Penicillium canescens

Process Biochemistry, 2014
Abstract Under the deacetylation of fungal endophyte Penicillium canescens , which was isolated from pigeon pea, a novel and highly efficient biotransformation method of astragalosides to astragaloside IV in Radix Astragali was investigated. After single factor tests of the biotransformation procedure, the optimum biotransformation conditions were ...
Mei-ling Yao   +7 more
openaire   +1 more source

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