Results 111 to 120 of about 1,135 (159)

Transplantation-Driven Microbial Shifts and Keystone Taxa Enhance Medicinal Ingredients in Astragalus mongholicus

Microorganisms
Root-associated microbes play a crucial role in plant growth, stress resistance and the accumulation of secondary metabolites. In this study, LC-MS analysis revealed that soil provenance exerts a decisive influence on the content of flavonoids and ...
Yanmei Li, Jiangying Huang, Xinrui Wang, Chenyuan Wang, Gehong Wei, Zhefei Li   +5 more
doaj   +1 more source

Proteomic characterization of the cellular response to chemopreventive triterpenoid astragaloside IV in human hepatocellular carcinoma cell line HepG2

, 2010
Triterpenoids are implicated in the chemoprevention of various cancers. Current challenge is to define the molecular mechanism underlying the chemopreventive activity of triterpenoids.
Zhang, Q, Han, Y, Rong, J, Wei, L, Qi, H, Lau, ASY   +5 more
core   +1 more source

Multidimensional Quality Evaluation of Drying Methods on the Bioactive Components and Antioxidant Activity of Astragalus membranaceus var. mongholicus Slices

Separations
This study systematically evaluated the effects of five drying methods (sun drying, freeze drying, shade drying, and hot air drying at 40 °C and 60 °C) on the multidimensional quality of Astragalus membranaceus var.
Feifan Leng, Jiale Wang, Lizhe Hu, Minmin Li, Yongwei Sun, Yonggang Wang, Jieyin Chen, Xiaofeng Dai, Bin Ma, Qing Lv, Zhiqiang Kong   +10 more
doaj   +1 more source

Effects of astragaloside IV on splenic RORγt, T-bet and Foxp3 mRNA expressions of EAE mice.

, 2013
All data are presented as mean±standard error of the mean.
Yan Gao (93649), Hongshuai Liu (466800), Yixin He (466799), Hongwei Wang (151141), Xiaojun Wu (466801), Zhengtao Wang (466802), Min Du (292028)   +6 more
core   +1 more source

Astragaloside IV is a potential natural neuroprotective agent for stroke: a review

Frontiers in Pharmacology
Stroke poses a severe threat to human health, with limited therapeutic options currently available. Astragaloside IV (AS-IV), a primary bioactive metabolite derived from Astragalus membranaceus, exhibits multifaceted pharmacological effects, including anti-inflammatory, anti-fibrotic, and antioxidative properties.
Zhang, Qiao-Li, Qin, Wen-Xiu, Li, Xiu-Juan, Zhang, Yun-Bo, Li, Ming, Xu, Jun-Feng, Mao, Zhong-Nan   +6 more
openaire   +3 more sources

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

International Journal of Molecular Medicine
Fibrosis is a maladaptive response of tissues or organs to adverse stresses, such as chronic inflammation, infection and mechanical injury. It further promotes parenchymal cell loss, abnormal myofibroblast proliferation and excessive extracellular matrix buildup, eventually triggering scar tissue hyperplasia or organ injury.
Wu, Mingyu, Li, Ke, Wu, Jiabin, Zhang, Qiuyu, Ma, Xiaotong, Dai, Wei, Gao, Haoyang, Ding, Xianyi, Wang, Wenhong, Xiao, Weihua   +9 more
openaire   +3 more sources

Mean plasma concentration–time profile in rat plasma after oral administration of bu-yang-huan-wu-tang extract for astragaloside I (A), astragaloside II (B), astragaloside IV (C), formononetin (D), ononin (E), calycosin (F), calycosin-7-O-β-D-glucoside (G), ligustilide (H) and paeoniflorin (I).

, 2013
Mean plasma concentration–time profile in rat plasma after oral administration of bu-yang-huan-wu-tang extract for astragaloside I (A), astragaloside II (B), astragaloside IV (C), formononetin (D), ononin (E), calycosin (F), calycosin-7-O-β-D-glucoside ...
Lie-Chwen Lin (304431), Lee-Hsin Shaw (309531), Tung-Hu Tsai (271408)   +2 more
core   +1 more source

Typical MRM chromatograms of rat plasma sample after administration of bu-yang-huan-wu-tang extract: (A) Astragaloside I; (B) Astragaloside II; (C) Astragaloside IV; (D) Formononetin; (E) Ononin; (F) Calycosin; (G) Calycosin-7-O-β-D-glucoside; (H) Ligustilide; (I) Paeoniflorin and (J) Digoxin (IS).

, 2013
Typical MRM chromatograms of rat plasma sample after administration of bu-yang-huan-wu-tang extract: (A) Astragaloside I; (B) Astragaloside II; (C) Astragaloside IV; (D) Formononetin; (E) Ononin; (F) Calycosin; (G) Calycosin-7-O-β-D-glucoside; (H ...
Lie-Chwen Lin (304431), Lee-Hsin Shaw (309531), Tung-Hu Tsai (271408)   +2 more
core   +1 more source

Effects of Radix Astragali on renal proximal tubular epithelial cells-induced monocytes differentiation

Linchuang shenzangbing zazhi, 2016
Objective Mononcytes differentiate into different phenotypes under different conditions:classic activation M1 and alternative activation M2.M1 macrophages secrete proinflammatory cytokines and chemokines,present antigen,participate in the forward immune ...
LI Qing, XU Ling-dong, JIANG Yan, LIU Li-hua, SHENG Mei-xiao, HUA Jian-wu   +5 more
doaj  

Cardiovascular protective effects of astragaloside IV

Journal of Chinese Pharmaceutical Sciences, 2013
Shuai Liu, Jinguo Zhang
openaire   +1 more source