Results 91 to 100 of about 1,135 (159)

Astragaloside IV promotes the eNOS/NO/cGMP pathway and improves left ventricular diastolic function in rats with metabolic syndrome

Journal of International Medical Research, 2020
Objectives This study aimed to explore the effects of astragaloside IV on metabolic syndrome induced by a high-fructose/high-fat diet in rats. Methods Rats were randomized into four groups: normal control, metabolic syndrome, metabolic syndrome ...
Xin Lin, Qiongying Wang, Shougang Sun, Guangli Xu, Qiang Wu, Miaomiao Qi, Feng Bai, Jing Yu   +7 more
doaj   +1 more source

Effects of astragaloside IV on apoptotic proteins.

, 2013
A, western blots of GFAP, Bcl-2, Bax, p53, p-tau in cortices of EAE mice treated with astragaloside IV. B-E, gray intensity analysis of GFAP, Bcl-2, Bax, p53 and p-tau. All data are presented as mean±standard error of the mean and compared with EAE group.
Yan Gao (93649), Hongshuai Liu (466800), Yixin He (466799), Hongwei Wang (151141), Xiaojun Wu (466801), Zhengtao Wang (466802), Min Du (292028)   +6 more
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Astragaloside Ⅳ mediates the effect and mechanism of KPNB1 on biological behavior and tumor growth in prostate cancer

Heliyon
Background: and purpose Prostate cancer is an comparatively prevalent clinical malignant tumor in men, impacting the lives of millions of men globally. This study measured the expression of Karyopherin Subunit Beta 1 (KPNB1) in prostate cancer cells, and
Quan Ma, Xiaojun Lu, Wei Tian, Yongliang Chen, Xiaozhou He   +4 more
doaj   +1 more source

Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats

, 2018
Xiao Lei, Limei Zhang, Zonglin Li, Jigang Ren Traditional Chinese Medicine Department, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan Province, People’s Republic of China Objective: This study aims to figure out the ...
Li Z, Lei X, Ren J, Zhang L
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The Astragaloside IV Derivative LS-102 Ameliorates Obesity-Related Nephropathy

Drug Design, Development and Therapy, 2022
Ziyu Li,1 Wei Yang,1 Yong Yang,1 Jianbo Wu,2 Pei Luo,3 Yong Liu1,4,5 1Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Drug Discovery Research Center, Southwest Medical ...
Li Z, Yang W, Yang Y, Wu J, Luo P, Liu Y
doaj  

Structure formula of 9 components in bu-yang-huan-wu-tang extract of astragaloside I (A), astragaloside II (B), astragaloside IV (C), formononetin (D), ononin (E), calycosin (F), calycosin-7-O-β-D-glucoside (G), ligustilide (H) and paeoniflorin (I).

, 2013
Structure formula of 9 components in bu-yang-huan-wu-tang extract of astragaloside I (A), astragaloside II (B), astragaloside IV (C), formononetin (D), ononin (E), calycosin (F), calycosin-7-O-β-D-glucoside (G), ligustilide (H) and paeoniflorin (I).
Lie-Chwen Lin (304431), Lee-Hsin Shaw (309531), Tung-Hu Tsai (271408)   +2 more
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Effects of different drying temperature on the contents of CG, ononin, calycosin, formononetin and astragaloside IV in AR pieces.

, 2022
Effects of different drying temperature on the contents of CG, ononin, calycosin, formononetin and astragaloside IV in AR pieces.
Lifang Ye (9858938), Mengmei Wu (10691354), Zhiguo Ma (842755), Hui Cao (182176), Menghua Wu (333208), Jie Peng (188267), Ying Zhang (40767)   +6 more
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Diagram illustrates the potential actions of Astragaloside IV on Fas/Fas L apoptotic pathway.

, 2014
Astragaloside IV appear to block the cleavage of procaspase-8. As a result of the actions of Astragaloside IV, the release of Cyt c is inhibited, resulting in decreases of procaspase-9 and caspase-3.
Woong Mo Yang (543924), Mi Hye Kim (543923), Sung-Hoon Kim (41182)   +2 more
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Astragaloside IV Attenuated 3,4-Benzopyrene-Induced Abdominal Aortic Aneurysm by Ameliorating Macrophage-Mediated Inflammation

Frontiers in Pharmacology, 2018
Abdominal aortic aneurysm (AAA), characterized by macrophage infiltration-mediated inflammation and oxidative stress, is a potentially fatal disease. Astragaloside IV (AS-IV) has been acknowledged to exhibit antioxidant and anti-inflammatory properties ...
Jiaoni Wang, Yingying Zhou, Shaoze Wu, Kaiyu Huang, Saroj Thapa, Luyuan Tao, Jie Wang, Yigen Shen, Jinsheng Wang, Yangjing Xue, Kangting Ji   +10 more
doaj   +1 more source

Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB P65 subunit

, 2018
Xiaolei Wang,1,2 Yanbin Gao,1,2 Nianxiu Tian,1 Zhiyao Zhu,2 Tao Wang,1 Jiayi Xu,1 Bingjie Wu,1 Nan Zhang2 1Department of Endocrinology, School of Traditional Chinese Medicine, Capital Medical University, Beijing, China; 2Department of Endocrinology ...
Zhu Z, Wang T, Gao Y, Wu B, Zhang N, Wang X, Tian N, Xu J   +7 more
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