Results 81 to 90 of about 1,135 (159)

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Astragaloside IV protects rat retinal capillary endothelial cells against high glucose-induced oxidative injury

, 2017
Yuan Qiao, Chun-Lan Fan, Min-Ke Tang School of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang District, Beijing, People’s Republic of China Aim: Diabetic retinopathy is a microvascular complication of diabetes that leads
Qiao Y, Tang M, Fan C
core  

Astragaloside IV, a saponin from Astragalus membranaceus var. mongholicus, induces expressions of heme recycle proteins via signaling of Nrf2/ARE in cultured macrophages

, 2021
Ethnopharmacological relevance: In traditional Chinese medicine (TCM) theory, “Qi” is classified as energetic essence supporting the life activities in human. “Blood” is categorized as nourishing essence and circulating in the body. “Blood” and “Qi” have
Yu, Huiru, Gong, Guowei, Dong, Tina TX, Tsim, Karl WK, Zheng, Yuzhong, Yin, Tianpeng, Qi, Baohui, He, Huan   +7 more
core   +1 more source

Identification of Quality Markers in Viola kunawaresis Royel Using HPLC Fingerprints, Chemometric Analysis, and Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 4, April 2026.
ABSTRACT Violae tianshanicae herba (VTH), a widely used crude drug in Uyghur medicine in China, is renowned for its immunomodulatory, anti‐inflammatory, antibacterial, antiviral, and antidiabetic activities, with notable efficacy in treating asthma. However, systematic research on its quality markers (Q‐markers) remains limited, underscoring the need ...
Haifeng Liu, Rongmei Zhao, Hong Xu, Tabusi Manaer, Le Pan, Lu Jin, Amatjan Ayupbek   +6 more
wiley   +1 more source

Astragalus IV Undermines Multi-Drug Resistance and Glycolysis of MDA-MB-231/ADR Cell Line by Depressing hsa_circ_0001982-miR-206/miR-613 Axis

Cancer Management and Research, 2021
Hongchang Li,1,* Zhihua Xia,2,* Limin Liu,3,* Gaofeng Pan,1 Junbin Ding,1 Jiazhe Liu,1 Jie Kang,1 Jindong Li,1 Daowen Jiang,1 Weiyan Liu1 1Department of General Surgery, Institute of Fudan-Minhang Academic Health System, Minhang Hospital ...
Li H, Xia Z, Liu L, Pan G, Ding J, Liu J, Kang J, Li J, Jiang D, Liu W   +9 more
doaj  

Alternative Approaches and Plant‐Based Remedies for Livestock Health Management Among the Batswana of Southern Africa: A Review

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT Due to limited access to, and the high cost of conventional veterinary services, Batswana communities often rely on ethnoveterinary practices for livestock health management. This review provides an in‐depth analysis on the ethnoveterinary uses, biological properties and safety assessment of plants utilised in livestock husbandry. A systematic
Tswelelopele G. Mpolokeng, Ndzalama Shikwambana, Mompati V. Chakale, John A. Asong, Lyndy J. McGaw, Stephen O. Amoo, Nqobile A. Masondo, Adeyemi O. Aremu   +7 more
wiley   +1 more source

The mechanism of astragaloside IV promoting sciatic nerve regeneration.

Neural regeneration research, 2013
3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosyl-cycloastragenol (astragaloside IV), the main active component of the traditional Chinese medicine astragalus membranaceus, has been shown to be neuroprotective. This study investigated whether astragaloside IV could promote the repair of injured sciatic nerve.
Zhang, Xiaohong, Chen, Jiajun
openaire   +2 more sources

Effects of Diet Strategy and Nutrients on the Progression and Prevention of Diabetic Cardiomyopathy: A Narrative Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng, Kai‐xuan Lin, Abdallah Iddy Chaurembo, Francis Chanda, Yuan Li, Li‐Dan Fu, Hao‐Dong Cui, Xin‐Yue Tong, Chi Shu, Han‐Bin Lin   +9 more
wiley   +1 more source

Effects of Astragaloside IV on pattern ERG outcomes.

, 2014
Data are expressed as the mean ± SD. A. Pattern ERG amplitudes in all groups.
Songtao Yuan (291486), Qinghuai Liu (5314640), Qinglu Song (490434), Dongqing Yuan (5659165), Yuan Fang (132924), Pingan Mao (664158), Xiaoyi Liu (572510), Ping Xie (112003), Rihua Zhang (207627), Yun Liu (84346), Yuzhi Ding (664157), Chen Zhao (225070), Qiong Huang (156409)   +12 more
core   +1 more source