Results 91 to 100 of about 181,113 (262)
Induced Remodelling of Astrocytes In Vitro and In Vivo by Manipulation of Astrocytic RhoA Activity
Cells, 2023 Structural changes of astrocytes and their perisynaptic processes occur in response to various physiological and pathophysiological stimuli. They are thought to profoundly affect synaptic signalling and neuron-astrocyte communication.
Cátia Domingos +8 more
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Brain SciencesTinnitus is correlated with anomalies of neural plasticity and has been found to be affected by inflammatory status. The current theories on tinnitus, although still somewhat incomplete, are based on maladaptive plasticity mechanisms. Astrocytes play a major role in both neural responses to inflammation and plasticity regulation; moreover, they have ...
Paola Perin, Roberto Pizzala
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TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte–tracheal interactions
eLife, 2020 Astrocytes exhibit spatially-restricted near-membrane microdomain Ca2+transients in their fine processes. How these transients are generated and regulate brain function in vivo remains unclear. Here we show that Drosophila astrocytes exhibit spontaneous,
Zhiguo Ma, Marc R Freeman
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Astrocyte-Integrated Dynamic Function Exchange in Spiking Neural Networks [PDF]
arXiv, 2023 This paper presents an innovative methodology for improving the robustness and computational efficiency of Spiking Neural Networks (SNNs), a critical component in neuromorphic computing. The proposed approach integrates astrocytes, a type of glial cell prevalent in the human brain, into SNNs, creating astrocyte-augmented networks.
arxiv
Mapping the spatiotemporal dynamics of calcium signaling in cellular neural networks using optical flow [PDF]
, 2010 An optical flow gradient algorithm was applied to spontaneously forming net- works of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling with single pixel resolution.
A. Cornell-Bell +37 more
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Astrocytes: biology and pathology [PDF]
Acta Neuropathologica, 2009 Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They contiguously tile the entire central nervous system (CNS) and exert many essential complex functions in the healthy CNS. Astrocytes respond to all forms of CNS insults through a process referred to as reactive astrogliosis, which has become a pathological hallmark of ...
Sofroniew, Michael V., Vinters, Harry V.
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Pathology and Astrocytes in Autism
Neuropsychiatric Disease and Treatment, 2023 A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal studies have focused on investigating the role of neurons in ASD. However, recent studies have hinted that glial cell pathology could be a characteristic of ASD.
Vakilzadeh,Gelareh +1 more
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ASN Neuro, 2020 Norepinephrine (NE) control of hypothalamic gluco-regulation involves astrocyte-derived energy fuel supply. In male rats, exogenous NE regulates astrocyte glycogen metabolic enzyme expression in vivo through 5’-AMP-activated protein kinase (AMPK ...
Mostafa M. H. Ibrahim +3 more
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Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]
, 2017 Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
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Astrocytes: Powering Memory [PDF]
Cell, 2011 Creating long-term memory requires a cellular program in neurons involving gene expression, protein synthesis, and formation of new synaptic connections. Suzuki et al. (2011) show that astrocytes, glial cells of the brain, play a necessary role in this program by converting glycogen to lactate and transporting it to neurons.
Bezzi Paola, Volterra Andrea
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