Results 171 to 180 of about 31,071 (248)

Targeted neuronal stimulation modulates working memory via astrocytic interactions: Insights from a spiking neuron-astrocyte model. [PDF]

iScience
Naghieh P, Amiri M, Peremans H.
europepmc   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Plcg2 Deficiency Leads to Sex-Associated Divergent Effects on Glial Transcriptomes. [PDF]

Glia
Hartigan KA, Dabin LC, Kersey HN, Jury-Garfe N, Sharify AD, Kim B, Lamb BT, Bissel SJ, Lasagna-Reeves C, Kim J.   +9 more
europepmc   +1 more source

Prefrontal Planning Latency Associated With Age and Serological Evidence of Microbial Exposure

Chronic Diseases and Translational Medicine, EarlyView.
Planning latency versus age by group. Scatterplot showing individual observations (n = 53) stratified by fibromyalgia status. LOESS smoothing curves with 95% confidence intervals (shaded regions) illustrate the relationship within each group. Overall, rₛ = 0.394 (p = 0.003).
Basant K. Puri, Rosemarie Preyer, Gary S. Lee, Lucy Monaghan, Armin Schwarzbach   +4 more
wiley   +1 more source

Azoimidazolium Salts as a Platform for Persistent Neutral Aminyl Radicals and Mesoionic Carbene Au(I) Complexes as Cell‐Permeable Fluorophores

Chemistry – A European Journal, EarlyView.
Strategic electronic matching between imidazolium salts and aryldiazonium salts enables a chromatography‐free route to versatile azoimidazolium scaffolds. Fine‐tuning the substituents unveils a powerful dichotomy: strong ─OMe resonance stabilizes highly persistent neutral aminyl radicals (up to 3 weeks), whereas the superior ─NMe2 donor strength yields
Diego Dusso, Osvaldo F. López‐Saladino, Ixsoyen F. Vázquez‐Sandoval, Arturo Jiménez‐Sánchez, Virginia Gómez‐Vidales, Marcos Flores‐Álamo, Susana Porcel‐García   +6 more
wiley   +1 more source

Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework. [PDF]

Mol Biol Rep
Chen W, Teng H, Yang X, Gao F, Han C, Yang S, Zhou H, Yang Z.   +7 more
europepmc   +1 more source

KIF1A‐Mediated Axonal Transport of Netrin‐1 in iPSC‐Derived Human Forebrain Neurons

Cytoskeleton, EarlyView.
ABSTRACT Netrin‐1 is a secreted laminin‐like protein that functions as a guidance cue for axon pathfinding in development. Netrin‐1 also modulates synapse formation in developing neurons and long‐term potentiation in mature neurons. Netrin‐1 is expressed in human neurons; however, its intracellular distribution and trafficking have not been assessed ...
T. Y. Leung, J. Sidhu, A. Hsieh, Y. Ma, J. Liu, M. A. Silverman   +5 more
wiley   +1 more source

Swelling-induced calcium signaling in wild-type and <i>Mlc1</i>-null astrocytes: paradoxical effects of pharmacological TRPV4 and Piezo1 inhibition. [PDF]

Front Cell Neurosci
Bisseling Q, Kuhnke V, Brignone MS, Ambrosini E, Mansvelder HD, van der Knaap MS, Min R.   +6 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source