Results 81 to 90 of about 1,396,802 (284)

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling [PDF]

, 2015
The occurrence of cognitive disturbances upon CNS inflammation or infection has been correlated with increased levels of the cytokine tumor necrosis factor-α (TNFα).
Kollias, G., Santello, Mirko, Suter, T., Zappia, G., Santello, M., Stubbe, H., Volterra, A., Stubbe, Hiltrud, Fontana, Adriano, Pryce, Christopher R, Klaus, Federica R, Habbas, S., Liaudet, Nicolas, Klaus, Federica R., Becker, D., Fontana, A., Zappia, Giovanna, Habbas, Samia, Liaudet, N., Pryce, Christopher R., Klaus, F.R., Volterra, Andrea, Pryce, C.R., Becker, Denise, Kollias, George, Suter, Tobias   +25 more
core   +2 more sources

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

Advanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà, Giulia Cazzador, Roberta Fabbri, Matteo Calosi, Alessandro Silvestri, Andrea Candini, Fabiola Liscio, Franco Corticelli, Aikaterini Konstantoulaki, Andrea D'Iorio, Marco Caprini, Vincenzo Palermo, Monica Bertoldo, Valentina Benfenati, Chiara Zanardi, Emanuele Treossi   +15 more
wiley   +1 more source

Calcium signalling in astrocytes

, 1994
Bibliography: p. 188-218.
openaire   +2 more sources

Astrocytes sense glymphatic-level shear stress through the interaction of sphingosine-1-phosphate with Piezo1

iScience
Summary: Astrocyte endfeet enwrap brain vasculature, forming a boundary for perivascular glymphatic flow of fluid and solutes along and across the astrocyte endfeet into the brain parenchyma.
Antonio Cibelli, David Ballesteros-Gomez, Sean McCutcheon, Greta L. Yang, Ashley Bispo, Michael Krawchuk, Giselle Piedra, David C. Spray   +7 more
doaj   +1 more source

A Computational Model of Interactions Between Neuronal and Astrocytic Networks: The Role of Astrocytes in the Stability of the Neuronal Firing Rate

Frontiers in Computational Neuroscience, 2020
Recent research in neuroscience indicates the importance of tripartite synapses and gliotransmission mediated by astrocytes in neuronal system modulation.
Kerstin Lenk, Eero Satuvuori, Eero Satuvuori, Eero Satuvuori, Eero Satuvuori, Jules Lallouette, Jules Lallouette, Antonio Ladrón-de-Guevara, Hugues Berry, Hugues Berry, Jari A. K. Hyttinen   +10 more
doaj   +1 more source

Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia [PDF]

, 2013
Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions.
Kasimov, V, Gourine, A, Patrushev, M, Marina, N, Castaldo, C, Kasparov, Sergey, Larina, O   +6 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The role of glia in protein misfolding diseases

, 2010
The astrocytes, oligodendrocytes and microglia make up a significant proportion of the cells of the CNS. In recent years, there has been a burgeoning interest in the role of glial cells, in neurodegenerative disease.
Samson, Ben
core   +1 more source

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

Advanced NanoBiomed Research
Astrocyte ion channels, water channels, and calcium signaling play vital roles in maintaining brain homeostasis, coordinating neural network activity, supporting cognitive functions, and mediating neurovascular coupling. Disruptions in astrocyte dynamics
Roberta Fabbri, Karima Jeneh Perry, Emanuela Saracino, Chiara Lazzarini, Anna Mariano, Diletta Spennato, Maria Grazia Mola, Maria Grazia Raucci, Alessandro Kovtun, Marianna Barbalinardo, Giorgia Conte, Denis Gentili, Marco Caprini, Vincenzo Palermo, Roberto Zamboni, Luigi Ambrosio, Wolfgang Losert, Andrea Candini, Grazia Paola Nicchia, Raj K. Gupta, Valentina Benfenati, Shashi P. Karna   +21 more
doaj   +1 more source