Results 111 to 120 of about 123,114 (319)
Dual roles of astrocytes in plasticity and reconstruction after traumatic brain injury
Cell Communication and Signaling, 2020 Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide. Despite its high prevalence, effective treatment strategies for TBI are limited.
Yunxiang Zhou +5 more
semanticscholar +1 more source
Advanced Materials, Volume 37, Issue 13, April 2, 2025.A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
wiley +1 more source
Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease
AGING MEDICINE, Volume 5, Issue 4, Page 272-280, December 2022., 2022 Amyloid plaques deposit on neurons in case of Alzheimer's Disease. Mitochondria play a vital role in pathogenesis of Alzheimer's Disease. Mitochondrial dysfunction can lead to formation of mPTP, alteration of complexes 1,3 and 4, deficits in bioenergetics with impaired mitochondrial biogenesis. Abstract It is widely recognized that Alzheimer's disease (
Faizan Ahmad, Punya Sachdeva
wiley +1 more source
Astrocytes: Role and Functions in Brain Pathologies
Frontiers in Pharmacology, 2019 Astrocytes are a population of cells with distinctive morphological and functional characteristics that differ within specific areas of the brain. Postnatally, astrocyte progenitors migrate to reach their brain area and related properties.
R. Siracusa, R. Fusco, S. Cuzzocrea
semanticscholar +1 more source
Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow
Nature Communications, 2020 Astrocytes provide neurons with essential metabolic and structural support, modulate neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to sense conditions of potential metabolic insufficiency. Here we show that
N. Marina +13 more
semanticscholar +1 more source
Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Differentiation of astrocytes from human pluripotent stem cells (hPSCs) is a tedious and variable process. This hampers the study of hPSC-generated astrocytes in disease processes and drug development.
Xiang Li +13 more
doaj
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Computational Astrocyence: Astrocytes encode inhibitory activity into the frequency and spatial extent of their calcium elevations [PDF]
arXiv, 2019 Deciphering the complex interactions between neurotransmission and astrocytic $Ca^{2+}$ elevations is a target promising a comprehensive understanding of brain function. While the astrocytic response to excitatory synaptic activity has been extensively studied, how inhibitory activity results to intracellular $Ca^{2+}$ waves remains elusive.
arxiv
Advanced Materials Interfaces, EarlyView.An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki +6 more
wiley +1 more source
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain
Journal of Neuroinflammation, 2020 Background Many lines of evidence suggest that accumulation of aggregated alpha-synuclein (αSYN) in the Parkinson’s disease (PD) brain causes infiltration of T cells.
Jinar Rostami +7 more
semanticscholar +1 more source