Results 51 to 60 of about 462,755 (380)
Activation of Egr-1 expression in astrocytes by HIV-1 Tat: new insights into astrocyte-mediated Tat neurotoxicity [PDF]
, 2011 Human immunodeficiency virus type 1 (HIV-1) Tat plays an important role in HIV-associated neuropathogenesis; the underlying mechanisms are still evolving. We have recently shown that HIV-1 Tat induces expression of glial fibrillary acidic protein (GFAP),
Fan, Yan +4 more
core +1 more source
Astrocytes: a double-edged sword in neurodegenerative diseases
Neural Regeneration Research, 2021 Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by regulating homeostasis, increasing synaptic plasticity, and sustaining neuroprotective effects.
Z. Ding +5 more
semanticscholar +1 more source
Active sulforhodamine 101 uptake into hippocampal astrocytes. [PDF]
PLoS ONE, 2012 Sulforhodamine 101 (SR101) is widely used as a marker of astrocytes. In this study we investigated labeling of astrocytes by SR101 in acute slices from the ventrolateral medulla and the hippocampus of transgenic mice expressing EGFP under the control of ...
Christian Schnell +2 more
doaj +1 more source
Astrocytic LRP1 mediates brain Aβ clearance and impacts amyloid deposition [PDF]
, 2017 Accumulation and deposition of amyloid-β (Aβ) in the brain represent an early and perhaps necessary step in the pathogenesis of Alzheimer's disease (AD).
Bu, Guojun +8 more
core +2 more sources
From Synapses to Circuits, Astrocytes Regulate Behavior
Frontiers in Neural Circuits, 2022 Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior. Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes influence synapse formation, function, and plasticity.
Krissy A. Lyon, N. J. Allen
semanticscholar +1 more source
Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]
, 1981 We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith +18 more
core +1 more source
Crosstalk Between Astrocytes and Microglia: An Overview
Frontiers in Immunology, 2020 Based on discoveries enabled by new technologies and analysis using novel computational tools, neuroscience can be re-conceived in terms of information exchange in dense networks of intercellular connections rather than in the context of individual ...
A. Matejuk, R. Ransohoff
semanticscholar +1 more source
Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. [PDF]
, 2013 Postnatal/adult neural stem cells (NSCs) within the rodent subventricular zone (SVZ; also called subependymal zone) generate doublecortin (Dcx)(+) neuroblasts that migrate and integrate into olfactory bulb circuitry.
Abdi, Khadar +9 more
core +1 more source
Cells, 2019 Glutamate is one of the most prevalent neurotransmitters released by excitatory neurons in the central nervous system (CNS); however, residual glutamate in the extracellular space is, potentially, neurotoxic.
Shaimaa S. Mahmoud +3 more
semanticscholar +1 more source
Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells
Stem Cell Reports, 2018 Summary: Differentiation of astrocytes from human pluripotent stem cells (hPSCs) is a tedious and variable process. This hampers the study of hPSC-generated astrocytes in disease processes and drug development.
Xiang Li +13 more
doaj +1 more source