Results 41 to 50 of about 108,676 (277)
Enantioselective synthesis and application to the allylic imidate rearrangement of amine-coordinated palladacycle catalysts of cobalt sandwich complexes [PDF]
The reaction of (η5-(N,N-dimethylaminomethyl)cyclopentadien-yl)(η4-tetraphenylcyclobutadiene)cobalt with sodium tetrachloropalladate and (R)-N-acetylphenylalanine gave planar chiral palladacycle di-μ-chloridebis[(η5-(Sp)-2-(N,N-dimethylaminomethyl ...
Cassar, Doyle J. +5 more
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Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years
Human immunodeficiency virus (HIV) is the primary infectious agent of acquired immunodeficiency syndrome (AIDS), and non-nucleoside reverse transcriptase inhibitors (NNRTIs) are the cornerstone of HIV treatment.
Chunlin Zhuang +3 more
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The introduction of new interactions into organic transformation is an objective of fundamental importance. Chalcogen bond has emerged as an unconventional type of noncovalent interaction which provides a useful synthetic tool for organocatalysis and has
Weitao Yan +3 more
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Total Synthesis of Natural Terpenoids Enabled by Cobalt Catalysis
Transition metal catalysis plays an essential role in the total synthesis of natural products. Cobalt-mediated asymmetric catalysis has successfully been used as a primary or a secondary step in the total synthesis of natural products, especially ...
Shu Xiao +6 more
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Organocatalytic synthesis of axially chiral atropisomers [PDF]
This review summarises the recent progress made in the organocatalytic synthesis of atropisomeric compounds. Methodologies based on dynamic kinetic resolution and direct access to BINOL-like biaryls are described.
Renzi, P.
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Asymmetric catalysis in synthetic strategies for chiral benzothiazepines
Chiral benzothiazepines constitute the core structures of many foremost pharmaceuticals with diverse biological activities endowed by their unique scaffolds, which poses a great challenge to organic chemists and pharmaceutical researchers.
Haifeng Wang +4 more
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Asymmetric catalysis has continued to enable the preparation of optically active natural products over the past decade. This minireview summarizes progress in the catalytic enantioselective total synthesis of complex monoterpenoid indole alkaloids ...
Xiao-Yu Liu, Yong Qin
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Enantioselective Organo-Cascade Catalysis [PDF]
A new strategy for organocatalysis based on the biochemical blueprints of biosynthesis has enabled a new laboratory approach to cascade catalysis. Imidazolidinone-based catalytic cycles, involving iminium and enamine activation, have been successfully ...
Huang, Yong +3 more
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Copper(I)-catalyzed asymmetric alkylation of α-imino-esters
Asymmetric alkylation of enolates is one of the most direct and important reactions to prepare α-chiral carbonyl compounds. Except for the classical methods that rely on the use of chiral auxiliaries, asymmetric catalysis emerged as a powerful tool ...
Zong-Ci Liu +3 more
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New Trends in Asymmetric Catalysis [PDF]
As far back as the mid-nineteenth century, the studies of Louis Pasteur brought to light the essential role of molecular chirality in biology [...]
Schettini R., Sala G. D.
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