Results 41 to 50 of about 108,676 (277)

Enantioselective synthesis and application to the allylic imidate rearrangement of amine-coordinated palladacycle catalysts of cobalt sandwich complexes [PDF]

open access: yes, 2013
The reaction of (η5-(N,N-dimethylaminomethyl)cyclopentadien-yl)(η4-tetraphenylcyclobutadiene)cobalt with sodium tetrachloropalladate and (R)-N-acetylphenylalanine gave planar chiral palladacycle di-μ-chloridebis[(η5-(Sp)-2-(N,N-dimethylaminomethyl ...
Cassar, Doyle J.   +5 more
core   +1 more source

Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

open access: yesActa Pharmaceutica Sinica B, 2020
Human immunodeficiency virus (HIV) is the primary infectious agent of acquired immunodeficiency syndrome (AIDS), and non-nucleoside reverse transcriptase inhibitors (NNRTIs) are the cornerstone of HIV treatment.
Chunlin Zhuang   +3 more
doaj   +1 more source

Harnessing noncovalent interaction of chalcogen bond in organocatalysis: From the catalyst point of view

open access: yesGreen Synthesis and Catalysis, 2021
The introduction of new interactions into organic transformation is an objective of fundamental importance. Chalcogen bond has emerged as an unconventional type of noncovalent interaction which provides a useful synthetic tool for organocatalysis and has
Weitao Yan   +3 more
doaj   +1 more source

Total Synthesis of Natural Terpenoids Enabled by Cobalt Catalysis

open access: yesFrontiers in Chemistry, 2022
Transition metal catalysis plays an essential role in the total synthesis of natural products. Cobalt-mediated asymmetric catalysis has successfully been used as a primary or a secondary step in the total synthesis of natural products, especially ...
Shu Xiao   +6 more
doaj   +1 more source

Organocatalytic synthesis of axially chiral atropisomers [PDF]

open access: yes, 2017
This review summarises the recent progress made in the organocatalytic synthesis of atropisomeric compounds. Methodologies based on dynamic kinetic resolution and direct access to BINOL-like biaryls are described.
Renzi, P.
core   +1 more source

Asymmetric catalysis in synthetic strategies for chiral benzothiazepines

open access: yesGreen Synthesis and Catalysis, 2020
Chiral benzothiazepines constitute the core structures of many foremost pharmaceuticals with diverse biological activities endowed by their unique scaffolds, which poses a great challenge to organic chemists and pharmaceutical researchers.
Haifeng Wang   +4 more
doaj   +1 more source

Recent advances in the total synthesis of monoterpenoid indole alkaloids enabled by asymmetric catalysis

open access: yesGreen Synthesis and Catalysis, 2022
Asymmetric catalysis has continued to enable the preparation of optically active natural products over the past decade. This minireview summarizes progress in the catalytic enantioselective total synthesis of complex monoterpenoid indole alkaloids ...
Xiao-Yu Liu, Yong Qin
doaj   +1 more source

Enantioselective Organo-Cascade Catalysis [PDF]

open access: yes, 2005
A new strategy for organocatalysis based on the biochemical blueprints of biosynthesis has enabled a new laboratory approach to cascade catalysis. Imidazolidinone-based catalytic cycles, involving iminium and enamine activation, have been successfully ...
Huang, Yong   +3 more
core   +1 more source

Copper(I)-catalyzed asymmetric alkylation of α-imino-esters

open access: yesNature Communications, 2023
Asymmetric alkylation of enolates is one of the most direct and important reactions to prepare α-chiral carbonyl compounds. Except for the classical methods that rely on the use of chiral auxiliaries, asymmetric catalysis emerged as a powerful tool ...
Zong-Ci Liu   +3 more
doaj   +1 more source

New Trends in Asymmetric Catalysis [PDF]

open access: yesCatalysts, 2021
As far back as the mid-nineteenth century, the studies of Louis Pasteur brought to light the essential role of molecular chirality in biology [...]
Schettini R., Sala G. D.
openaire   +2 more sources

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