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The genomic organization of the rat AT1 angiotensin receptor
Biochemical and Biophysical Research Communications, 1992The AT1 receptor subtype modulates all of the hemodynamic effects of the vasoactive peptide, angiotensin II. In this report, we investigate the genomic organization of this important receptor. A rat genomic library was screened with fragments from the 5' region of a previously cloned cDNA, pCa18b, encoding the rat AT1 receptor.
K, Langford +3 more
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Therapeutic Effects of Angiotensin (AT1) Receptor Antagonists
American Journal of Cardiovascular Drugs, 2004Blockade of the renin-angiotensin system improves morbidity and mortality of patients with cardiovascular diseases, e.g. arterial hypertension, renal failure, following myocardial infarction and in congestive heart failure. The angiotensin II type 1 (AT(1)) receptor antagonists (angiotensin receptor blockers; ARBs), i.e.
Boris, Schmidt +2 more
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AT1 Receptor Antagonists: Pharmacology
2004Innovative chemical modifications of the first nonpeptide imidazole antagonist of Ang II led to the synthesis of various new orally active agents with increased potency and improved bioavailability (13%-80%). They block specifically and selectively the angiotensin ATI receptor without intrinsic agonist properties. The angiotensin receptor blockers (ARB)
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The Vascular Angiotensin (AT1) Receptor
Thrombosis and Haemostasis, 1993K K, Griendling +2 more
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Regulation of the angiotensin AT1 receptor by hypercholesterolaemia
Diabetes, Obesity and Metabolism, 2000G, Nickenig, S, Wassmann, M, Böhm
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[AT1 receptor and AT2 receptor].
Nihon rinsho. Japanese journal of clinical medicine, 2007Teppei, Fujita +2 more
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Autoantibodies against AT1-Receptor and .ALPHA.1-Adrenergic Receptor in Patients with Hypertension.
Hypertension Research, 2002Yu-Hua Liao +2 more
exaly
Six Commercially Available Angiotensin II AT1 Receptor Antibodies are Non-specific
Cellular and Molecular Neurobiology, 2012Julius Benický +2 more
exaly