Results 201 to 210 of about 31,889 (263)

Sexually dimorphic ATF4 expression in the fat confers female stress tolerance in Drosophila melanogaster. [PDF]

Genetics
Grmai L, Mychalczuk M, Arkalgud A, Vasudevan D.   +3 more
europepmc   +1 more source

HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis. [PDF]

PLoS One
Jiang P, Wang H, Li Y, Zhang Y, Huang J, Xu Y, Rong D, Ruan D, Wang Y, Yuan J, Li P.   +10 more
europepmc   +1 more source

Cox10-mediated mitochondrial respiration in brown adipocytes regulates adaptive thermogenesis and systemic metabolism. [PDF]

iScience
Paulo E, Wu Y, Wang B.
europepmc   +1 more source

Distinct cell type-specific mechanisms underlie cognitive dysfunction during persistent integrated stress response activation. [PDF]

Proc Natl Acad Sci U S A
Torkenczy K, Reineke LC, Dooling SW, Henderson BW, Yang B, He D, Myers RM, Walter P, Tyanova S, Costa-Mattioli M.   +9 more
europepmc   +1 more source

KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion. [PDF]

Apoptosis
Criscuolo D, Catalano R, Baviello C, Fioravanti C, Vigliar E, Morra F, Marotta M, Mimura J, Iaccarino A, Pepe F, Belotti D, Troncone G, Merolla F, Melillo RM, Celetti A.   +14 more
europepmc   +1 more source

Immune checkpoint inhibitor-driven smooth muscle cell phenotypic modulation: a potential contributor to atherosclerotic risk associated with these therapies. [PDF]

Front Cardiovasc Med
Chattopadhyay A, Dosunmu AO, Reddy D, Dharma S, Panchal K, Kwartler CS, Milewicz DM.   +6 more
europepmc   +1 more source

ATF4: Orchestrating Cellular Stress Adaptation, Metabolism, and Immune Regulation in Health and Disease. [PDF]

Int J Mol Sci
Wang C, Jia F, He F.
europepmc   +1 more source

<i>Salmonella</i> Typhi asparaginase-dependent activation of GCN2 promotes bacterial killing in murine macrophages. [PDF]

Infect Immun
Powers ZM, McFadden MJ, Lee GY, Schultz T, Castro Jorge LA, Edwards DF, Sanchez-Paiva S, Sexton JZ, Spindler KR, Song J, O'Riordan MX.   +10 more
europepmc   +1 more source

Unfolding Resilience: Molecular Integration of the Integrated Stress Response and Mitochondrial UPR in Skeletal Muscle Homeostasis. [PDF]

Muscles
Sanfrancesco VC, Della Mea D, Hood DA.
europepmc   +1 more source

mTOR inhibition enhances the antitumor efficacy of pan-RAF-MEK blockade by inhibiting the ATF4-MTHFD2 pathway. [PDF]

Cell Death Dis
Cai F, Huang F, Goncalves C, Srikannan H, Gagnon N, Guettler EM, Mukeba-Harchies L, Maxwell J, Su J, Bijian K, Journe F, Rose AAN, Orthwein A, Del Rincón SV, Miller WH.   +14 more
europepmc   +1 more source