Results 191 to 200 of about 31,889 (263)

ATF4 coordinates amino acid and nucleotide synthesis with selective protein translation to ensure proper DNA replication timing in leukemia cells. [PDF]

Nat Commun
Huhn JM, Valin L, Basse M, Sokei J, Gabriel N, Martinez E, Kanefsky JS, Stransky S, Dorrance A, Garzon R, Di Marcantonio D, Skorski T, Goldman AR, Tang HY, Cortellazzi S, di Martino O, Krais J, Sidoli S, Ferraro F, Wiest DL, Sykes SM.   +20 more
europepmc   +1 more source

Ferroptosis‐Based Peripheral Immune Dysregulation and Diagnostic Signatures in Parkinson's Disease: An RNA Transcriptomic and Single‐Cell Immune Sequencing Analysis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng, Jing Zhang, Wen‐Ting Shi, Qing Ye, Chen Huang, Zhong‐Yan Zhou   +5 more
wiley   +1 more source

Etomidate Prevents Homocysteine‑Induced Endothelial Dysfunction by Suppressing PERK‑eIF2α‑ATF4 Signaling, Oxidative Stress, Mitochondrial Injury, and Autophagic Dysregulation. [PDF]

J Biochem Mol Toxicol
Song M, Tang H.
europepmc   +1 more source

Combined inhibition of de novo pyrimidine synthesis and ATR promotes ATF4-mediated cell death in <i>TP53</i>-deficient ALL. [PDF]

Hemasphere
Grünewald KJT, Kes MMG, Stoll GR, Cox WPJ, van Ingen Schenau DS, Scutigliani EM, Wagener EM, Tang Z, Visser S, Kooiman J, Buijs-Gladdines J, Rodionova M, Zaal EA, Jansen JWA, van Velzen JF, Drost J, van der Meer LT, Berkers CR, van Leeuwen FN.   +18 more
europepmc   +1 more source

ATF4 and CHOP coordinate endoplasmic reticulum stress-responsive gene programs through enhancer activation and chromatin looping. [PDF]

Nucleic Acids Res
Joo JS, Kim M, Kim S, Kim H, Kim HP.
europepmc   +1 more source

Targeting ATF4 overcomes dual resistance to chemo-immunotherapy in gastric cancer by disrupting the DNA damage response. [PDF]

J Immunother Cancer
Ye H, Zhang W, Cao H, Peng Z, Xu T, Xia Z, Li L, He N, Zhou Y, Qin J, Ma K, Ren W, Han H, Cai W, Qin L, Jiao Z.   +15 more
europepmc   +1 more source

KATP Channel Expression Determines ONC212 Sensitivity via Mitochondrial Dysfunction and PERK/ATF4/CHOP Activation in Glioblastoma. [PDF]

J Cell Mol Med
Taskesen A, Hacioglu C.
europepmc   +1 more source

Stress Responsive bZIP Transcription Factors ATF4 and BACH1 Cooperate With MAF-Family bZIP Protein NRL to Fine-Tune Rod Photoreceptor Gene Expression. [PDF]

Invest Ophthalmol Vis Sci
Preston K, Arya M, Kumari A, Nellissery J, Brooks MJ, Batz Z, Liang X, Tosini G, Swaroop A.   +8 more
europepmc   +1 more source

ATF4, ZIK1, and PNMA3 Transcriptomic Signatures Predict Chemoradiotherapy Response in Cervical Cancer. [PDF]

Cancer Med
de Melo Neto AB, Queiroz FR, de Souza Melo CP, Duarte BCD, Ferreira JGG, de Amorim IFG, do Amaral LR, Bertarini PLL, de Figueiredo Franco TMR, de Carvalho AT, Martins-Filho OA, de Jesus Jeremias W, da Conceição Braga L, de Oliveira Salles PG, de Souza Gomes M.   +14 more
europepmc   +1 more source

ATF4 promotes immune evasion in oral squamous cell carcinoma by suppressing autophagic PD-L1 degradation. [PDF]

J Immunother Cancer
Wang KM, Zhang LZ, Liang JJ, Wang Z, Wang XL, Zhang J, Chen G, Zhang W.   +7 more
europepmc   +1 more source