Results 21 to 30 of about 25,612 (182)

Autophagy activity and expression pattern of autophagy-related markers in the podocytes of patients with lupus nephritis: association with pathological classification

Renal Failure, 2019
Objective: To identify the significance of autophagy in lupus nephritis (LN). Methods: The number of autophagosomes in podocytes was counted and the expression of multiple molecular markers associated with autophagy was evaluated in LN specimens: in ...
Juan Jin, Qiudi Tu, Jianguang Gong, Li Zhao, Shikai Liang, Qiang He   +5 more
doaj   +1 more source

Essential role of ATG7 in LPS-induced endometrial inflammatory injury in goats

Animal Diseases, 2023
The economic losses caused by uterine infections in ruminants have received increasing attention. Autophagy-related 7 (ATG7) has been demonstrated to be capable of regulating apoptosis, but surprisingly, ATG7 can both promote and inhibit apoptosis in ...
Tingting Jiang, Xueting Yin, Jianguo Chen   +2 more
doaj   +1 more source

Knockdown of Atg7 suppresses Tumorigenesis in a murine model of liver cancer

Translational Oncology, 2021
Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer in adults and a leading cause of cancer-related deaths worldwide. Studies have shown that autophagy is significantly involved in carcinogenesis, in particular, driven by ...
Kyung Joo Cho, Sun Yeong Shin, Hyuk Moon, Beom Kyung Kim, Simon Weonsang Ro   +4 more
doaj   +1 more source

Z-cells and oogonia/oocytes in the advanced process of autophagy are the dominant altered cells in the ovaries of hypothyroid newborn rats

Acta Veterinaria, 2017
Induced prenatal hypothyroidism in rat pups leads to accelerated primordial follicle assembly and premature follicular atresia with ovary failure. This work investigates the influence of maternal hypothyroidism induced with 6-n-propyl-2-thyouracil (PTU ...
Danilović Luković Jelena, Korać Aleksandra, Milošević Ivan, Lužajić Tijana, Milanović Zorana, Kovačević Filipović Milica, Radovanović Anita   +6 more
doaj   +1 more source

Sevoflurane up-regulates miR-7a to protect against ischemic brain injury in rats by down-regulating ATG7 and reducing neuronal autophagy

Brain Research Bulletin, 2022
The current study aimed to elucidate the effects of Sevoflurane on neuronal autophagy and ischemic brain injury by regulating miR-7a/ATG7 axis. The rat model of middle cerebral artery occlusion (MCAO) was established by thread embolization.
Zhiguo Wu, Jian Tan, Lichang Lin, Wenting Zhang, Wanqiu Yuan   +4 more
doaj   +1 more source

Greining a hlutverki ATG7 ísóforma

, 2023
ATG7, an essential protein for cellular homeostasis, plays a pivotal role in regulating autophagy. The autophagy process ensures the degradation and recycling of cellular components for proper cell function.
Ostacolo, Kevin
core  

Silencing of ATG7 using the CMV VIGS system.

, 2023
(A) Flowchart of ATG7 silencing in N. benthamiana. A partial ATG7 sequence (190-nt) was inserted into the A1 vector (A1-ATG7), and the in vitro transcripts of CMV RNA1, RNA3 and the recombinant A1 were used to inoculate to N. benthamiana plants.
Shusuke Kawakubo (11807321), Hangil Kim (9751193), Chikara Masuta (222073), Haruna Takahashi (16462743)   +3 more
core   +1 more source

Lower ATG7 Levels are Associated with a Higher Risk of Gestational Diabetes Mellitus: A Cross-Sectional Study

Diabetes, Metabolic Syndrome and Obesity, 2022
Ling Lu,1 Yan Ma,2 Jie Deng,1 Jiaqiong Xie,1 Chaolin Huang1 1Department of Gynaecology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 2Department of Obstetrics, The First Affiliated Hospital of Chengdu ...
Lu L, Ma Y, Deng J, Xie J, Huang C
doaj  

Greining á hlutverki ATG7 í sjálfsátsóháðri frumustarfsemi

, 2020
Autophagy is a degradation process required for cellular homeostasis. The process is a means for the cell to retrieve energy and nutrients under stress conditions.
Sigríður Stefanía Hlynsdóttir 1991-
core   +2 more sources

Inhibition of ATG7 promotes orthodontic tooth movement by regulating the RANKL/OPG ratio under compression force

Open Medicine
Autophagy serves as a protective mechanism in response to mechanical stress during OTM. However, the role of ATG7, a key regulatory gene in autophagy, in modulating periodontium remodeling during OTM remains unclear.
Yang Zhenjin, Chen Mingzhu, Liao Xianmin, Ma Liya, Liang Cun, Li Yanjie, Hu Jiangtian   +6 more
doaj   +1 more source