Results 41 to 50 of about 39,511 (303)

Adipose Tissue Macrophages of the Human Fetus

open access: yesCells
Prenatal adipose tissue development affects body composition and growth trajectory in early infancy, therefore it is a key determinant of adiposity in childhood. Childhood overweight and obesity increase the probability of being obese as an adult.
Ádám Radványi   +5 more
doaj   +1 more source

MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling

open access: yesMolecular Metabolism, 2019
Objective: This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli. Methods: Macrophage-specific Dicer knockout (KO) mice were used
Yoon Keun Cho   +10 more
doaj   +1 more source

New Insights into Adipose Tissue Macrophages in Obesity and Insulin Resistance

open access: yesCells, 2022
Obesity has become a worldwide epidemic that poses a severe threat to human health. Evidence suggests that many obesity comorbidities, such as type 2 diabetes mellitus, steatohepatitis, and cardiovascular diseases, are related to obesity-induced chronic ...
Zhaohua Cai, Yijie Huang, Ben He
doaj   +1 more source

Too far ahead of its time: Barclays, Burroughs and real-time banking [PDF]

open access: yes, 2012
The historiography of computing has until now considered real-time computing in banking as predicated on the possibilities of networked ATMs in the 1970s. This article reveals a different story. It exposes the failed bid by Barclays and Burroughs to make
Martin, I
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Pop-up infrastructure: Water ATMs and new delivery networks in India

open access: yesWater Alternatives, 2020
Over the last decade, thousands of water ATMs have been installed across the Global South. In India, these vending machines increasingly augment both formal and informal networks of water supply and delivery. This article examines media reports on water
Jeremy J. Schmidt
doaj  

Designing on metamodels of air traffic management architecture modeling based on multi-frame modeling language [PDF]

open access: yesJournal of Intelligent Manufacturing and Special Equipment
Purpose – This paper aims to propose a set of metamodels applicable to the architecture modeling of air traffic management systems|air traffic management system (ATMS) under the UAF methodology.
Liu Tianning   +4 more
doaj   +1 more source

Adipose tissue macrophages in remote modulation of hepatic glucose production

open access: yesFrontiers in Immunology, 2022
Hepatic glucose production (HGP) is fine-regulated via glycogenolysis or gluconeogenesis to maintain physiological concentration of blood glucose during fasting-feeding cycle. Aberrant HGP leads to hyperglycemia in obesity-associated diabetes.
Yan Tao, Quanhong Jiang, Qun Wang
doaj   +1 more source

ATM meets ERK5

open access: yesAging, 2017
The complexity of the living cell is supported by the multitasking activity of its protein constituents. The kinase Ataxia Telangiectasia Mutated ATM)is a clear example. Not only does it orchestrate the DNA damage response but also sustains cellular homeostasis, including metabolism, control of oxidative stress, autophagy and apoptosis [1]. [...]
Angulo Ibáñez, María   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy