Results 61 to 70 of about 39,511 (303)

Symplectic quaternion scheme for biophysical molecular dynamics [PDF]

, 2002
Massively parallel biophysical molecular dynamics simulations, coupled with efficient methods, promise to open biologically significant time scales for study. In order to promote efficient fine-grained parallel algorithms with low communication overhead,
Eleftheriou, M., Martyna, G. J., Miller, T. F., III, Ndirango, A., Newns, D., Pattnaik, P.   +5 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Effect of Accelerated Transcranial Magnetic Stimulation on Insomnia Severity and Sleep Quality in Patients With Treatment-Resistant Depression [PDF]

Sleep Medicine Research
Background and Objective Insomnia severity and poor sleep quality are linked with a poor response to depression treatments. Furthermore, they may heighten suicide risk, necessitating careful management and treatment of insomnia.
Hilal Uygur, Rukiye Tekdemir, Hülya Ertekin   +2 more
doaj   +1 more source

Impacts of Assimilating ATMS Radiances on Heavy Rainfall Forecast in RMAPS-ST

Remote Sensing, 2020
The Advanced Technology Microwave Sounder (ATMS) mounted on the Suomi National Polar-Orbiting Partnership (NPP) satellite can provide both temperature and humidity information for a weather prediction model.
Yanhui Xie, Min Chen, Jiancheng Shi, Shuiyong Fan, Jing He, Youjun Dou   +5 more
doaj   +1 more source

The Campus Debit Card Trap: Are Bank Partnerships Fair to Students? [PDF]

, 2012
Examines partnerships between colleges and financial firms on campus ID, prepaid, debit, and financial aid disbursement cards and questions about fees, aggressive marketing strategies, and consumer protection.
Donna Cooper, Kristina Costa
core  

Search for a diffuse flux of astrophysical muon neutrinos with the IceCube 59-string configuration [PDF]

, 2013
A search for high-energy neutrinos was performed using data collected by the IceCube Neutrino Observatory from May 2009 to May 2010, when the array was running in its 59-string configuration. The data sample was optimized to contain muon neutrino induced
Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Altmann, D., Arguelles, C., Arlen, T. C., Auffenberg, J., Bai, X., Baker, M., Barwick, S. W., Baum, V., Bay, R., Beatty, J. J., Becker Tjus, J., Becker, K. -H., BenZvi, S., Berghaus, P., Berley, D., Bernardini, E., Bernhard, A., Besson, D. Z., Binder, G., Bindig, D., Bissok, Martin, Blaufuss, E., Blumenthal, Jan, Boersma, D. J., Bohm, C., Bose, D., Botner, O., Brayeur, L., Bretz, H. -P., Brown, A. M., Bruijn, R., Böser, S., Casey, J., Casier, M., Chirkin, D., Christov, A., Christy, B., Clark, K., Classen, L., Clevermann, F., Coenders, S., Cohen, S., Cowen, D. F., Cruz Silva, A. H., Danninger, M., Daughhetee, J., Davis, J. C., Day, M., de André, J. P. A. M., De Clercq, C., De Ridder, S., de Vries, K. D., de With, M., Desiati, P., DeYoung, T., Dunkman, M., Díaz-Vélez, J. C., Eagan, R., Eberhardt, B., Eichmann, B., Eisch, J., Euler, Sebastian, Evenson, P. A., Fadiran, O., Fazely, A. R., Fedynitch, A., Feintzeig, J., Feusels, T., Filimonov, K., Finley, C., Fischer-Wasels, T., Flis, S., Franckowiak, A., Frantzen, K., Fuchs, T., Gaisser, T. K., Gallagher, J., Gerhardt, L., Gladstone, L., Glüsenkamp, T., Goldschmidt, A., Golup, G., Gonzalez, J. G., Goodman, J. A., Grandmont, D. T., Grant, D., Gretskov, Pavel, Groh, J. C., Groß, A., Góra, D., Ha, C., Haj Ismail, A., Hallen, Patrick Bastian, Hallgren, A., Halzen, F., Hanson, K., Hebecker, D., Heereman, D., Heinen, Dirk, Helbing, K., Hellauer, R., Hickford, S., Hill, G. C., Hoffman, K. D., Hoffmann, R., Homeier, A., Hoshina, K., Huang, F., Huelsnitz, W., Hulth, P. O., Hultqvist, K., Hussain, S., IceCube Collaboration, Ishihara, A., Jacobi, E., Jacobsen, J., Jagielski, Kai, Japaridze, G. S., Jero, K., Jlelati, O., Kaminsky, B., Kappes, A., Karg, T., Karle, A., Kauer, M., Kelley, J. L., Kiryluk, J., Klein, S. R., Kläs, J., Kohnen, G., Kolanoski, H., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krasberg, M., Kriesten, A., Krings, K., Kroll, G., Kunnen, J., Kurahashi, N., Kuwabara, T., Köhne, J. -H., Köpke, L., Labare, M., Landsman, H., Larson, M. J., Lesiak-Bzdak, M., Leuermann, Martin, Leute, J., Lünemann, J., Macías, O., Madsen, J., Maggi, G., Maruyama, R., Mase, K., Matis, H. S., McNally, F., Meagher, K., Merck, M., Meures, T., Miarecki, S., Middell, E., Milke, N., Miller, J., Mohrmann, L., Montaruli, T., Morse, R., Nahnhauer, R., Naumann, U., Niederhausen, H., Nowicki, S. C., Nygren, D. R., O'Murchadha, A., Obertacke, A., Odrowski, S., Olivas, A., Omairat, A., Palczewski, T., Paul, Larissa, Pepper, J. A., Pfendner, C., Pieloth, D., Pinat, E., Posselt, J., Price, P. B., Przybylski, G. T., Pérez de los Heros, C., Quinnan, M., Rameez, M., Rawlins, K., Redl, P., Reimann, René, Resconi, E., Rhode, W., Ribordy, M., Richman, M., Riedel, B., Robertson, S., Rodrigues, J. P., Rott, C., Ruhe, T., Ruzybayev, B., Ryckbosch, D., Rädel, Leif, Saba, S. M., Sander, H. -G., Santander, M., Sarkar, S., Schatto, K., Scheriau, F., Schmidt, T., Schmitz, M., Schoenen, Sebastian, Schukraft, Anne, Schulte, L., Schulz, O., Schöneberg, S., Schönwald, A., Seckel, D., Sestayo, Y., Seunarine, S., Shanidze, R., Sheremata, C., Smith, M. W. E., Soldin, D., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stanisha, N. A., Stasik, A., Stezelberger, T., Stokstad, R. G., Strahler, E. A., Strotjohann, N. L., Ström, R., Stößl, A., Sullivan, G. W., Taavola, H., Taboada, I., Tamburro, A., Tepe, A., Ter-Antonyan, S., Tešić, G., Tilav, S., Toale, P. A., Tobin, M. N., Toscano, S., Tselengidou, M., Unger, E., Usner, M., Vallecorsa, S., van Eijndhoven, N., Van Overloop, A., van Santen, J., Vehring, Markus, Voge, M., Vraeghe, M., Walck, C., Waldenmaier, T., Wallraff, Marius, Weaver, Ch., Wellons, M., Wendt, C., Westerhoff, S., Whelan, B., Whitehorn, N., Wiebe, K., Wiebusch, Christopher, Williams, D. R., Wissing, H., Wolf, M., Wood, T. R., Woschnagg, K., Xu, D. L., Xu, X. W., Yanez, J. P., Yodh, G., Yoshida, S., Zarzhitsky, P., Ziemann, J., Zierke, Simon, Zoll, M.   +289 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restriction

Journal of Lipid Research, 2015
In addition to triacylglycerols, adipocytes contain a large reserve of unesterified cholesterol. During adipocyte lipolysis and cell death seen during severe obesity and weight loss, free fatty acids and cholesterol become available for uptake and ...
Hao Wei, Elizabeth J. Tarling, Timothy S. McMillen, Chongren Tang, Renée C. LeBoeuf   +4 more
doaj   +1 more source