Results 61 to 70 of about 9,220 (202)
Antimicrobial Agents and Chemotherapy, 2021 Atovaquone (AV) acts on the malaria parasite by competing with ubiquinol (UQH2) for its union to the mitochondrial bc1 complex, preventing the ubiquinone-8 and ubiquinone-9 (UQ-8 and UQ-9) redox recycling, which is a necessary step in pyrimidine ...
I. Verdaguer +9 more
semanticscholar +1 more source
ChemNanoMat, Volume 12, Issue 6, June 2026.Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo +3 more
wiley +1 more source
Malaria Journal, 2003 Background Resistance of Plasmodium falciparum to atovaquone in vitro and in vivo has been associated to mutations in the parasite cytochrome b gene. Methods Cultures were sequentially subjected to increasing doses of atovaquone alone or in combination ...
Salanti Ali +3 more
doaj +1 more source
Treatment of Human Babesiosis: Then and Now
Pathogens, 2021 Babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the genus Babesia. With its increasing incidence worldwide and the risk of human-to-human transmission through blood transfusion, babesiosis is becoming a rising public ...
Isaline Renard, Choukri Ben Mamoun
doaj +1 more source
Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus‐Associated Disorders
Cancer Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype. Case This case describes an antiretroviral therapy‐adherent person with HIV who presented with concurrent KSHV‐related disorders of Kaposi ...
Kandice Roberts +13 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesThe efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (MalaroneTM) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru.
A. Llanos-Cuentas +4 more
doaj +1 more source
eJHaem, Volume 7, Issue 3, June 2026.ABSTRACT Andersen–Tawil syndrome (ATS) is a rare, hereditary channelopathy characterized by periodic paralysis, cardiac arrhythmias, and sometimes developmental anomalies. No association with hematologic malignancies has previously been reported. We describe the case of a 27‐year‐old man with genetically confirmed Type 1 ATS who developed T‐cell acute ...
Ramy Rahmé +6 more
wiley +1 more source
Viruses, 2023 The emergence of SARS-CoV-1 in 2003 followed by MERS-CoV and now SARS-CoV-2 has proven the latent threat these viruses pose to humanity. While the SARS-CoV-2 pandemic has shifted to a stage of endemicity, the threat of new coronaviruses emerging from ...
Troy von Beck +6 more
doaj +1 more source
The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley +1 more source
Respirology Case Reports, Volume 14, Issue 6, June 2026.Pulmonary alveolar proteinosis (PAP) is an ultra‐rare lung disease that can recur even years after bilateral lung transplantation, as in this 73‐year‐old man whose diagnosis was delayed by PAS‐negative BAL and overlapping opportunistic infections (Nocardia, MAC, Aspergillus). Despite initially normal post‐transplant spirometry, he developed progressive
Omar Lopez +3 more
wiley +1 more source