Results 71 to 80 of about 9,220 (202)
Scientific Reports, 2020 The FDA-approved prophylactic antimalarial drug atovaquone (ATO) recently was repurposed as an antitumor drug. Studies show that ATO exerts a profound antiproliferative effect in several cancer cells, including breast, ovarian, and glioma.
Gang Cheng +6 more
semanticscholar +1 more source
A case of corneal opacity caused by atovaquone administration
American Journal of Ophthalmology Case ReportsPurpose: Atovaquone is an alternative drug that is used for the prevention and treatment of Pneumocystis pneumonia when the first-line drug, sulfamethoxazole-trimethoprim (ST combination), cannot be used due to side effects.
Takeyoshi Ashizuka +6 more
doaj +1 more source
Clinical Transplantation, Volume 40, Issue 6, June 2026.ABSTRACT Background Pneumocystis jirovecii is an opportunistic fungus responsible for Pneumocystis pneumonia (PJP) in hosts with impaired cell‐mediated immunity, particularly solid organ transplant recipients. The aim of our study was to identify risk factors associated with PJP in kidney transplant recipients (KTRs).
Solenne Hulot +9 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu +4 more
wiley +1 more source
Microsurgery, Volume 46, Issue 4, May 2026.ABSTRACT Limb salvage using free tissue transfer in patients with rare autoinflammatory syndromes is poorly described, and the safety of microvascular reconstruction in this population remains uncertain. Hereditary pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is characterized by dysregulated inflammation, pathergy, and impaired ...
Michael M. Talanker +9 more
wiley +1 more source
Reversible cerebral vasoconstriction syndrome: A narrative review
Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1162-1180, May 2026.Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa +7 more
wiley +1 more source
Drug Development Research, Volume 87, Issue 2, April 2026.ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu +7 more
wiley +1 more source
Cell Death Discovery, 2020 Platinum chemotherapies are highly effective cytotoxic agents but often induce resistance when used as monotherapies. Combinatorial strategies limit this risk and provide effective treatment options for many cancers.
J. Coates +9 more
semanticscholar +1 more source
Malaria Journal, 2011 The case of a 32-year-old Caucasian female with multi-drug resistant HIV-1 subtype B infection treated with a salvage regimen including maraviroc, raltegravir, etravirine and unboosted saquinavir who started atovaquone/proguanil prophylaxis, is reported.
Ivanovic Jelena +8 more
doaj +1 more source
Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging
VIEW, Volume 7, Issue 2, April 2026.Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao +8 more
wiley +1 more source