Results 1 to 10 of about 105,612 (201)
Human ATP-binding cassette (ABC) transporter family [PDF]
Human Genomics, 2009 There exist four fundamentally different classes of membrane-bound transport proteins: ion channels; transporters; aquaporins; and ATP-powered pumps. ATP-binding cassette (ABC) transporters are an example of ATP-dependent pumps.
Vasiliou Vasilis +2 more
doaj +3 more sources
ECF-Type ATP-Binding Cassette Transporters [PDF]
Annual Review of Biochemistry, 2019 Energy-coupling factor (ECF)–type ATP-binding cassette (ABC) transporters catalyze membrane transport of micronutrients in prokaryotes. Crystal structures and biochemical characterization have revealed that ECF transporters are mechanistically distinct from other ABC transport systems.
Rempel, S, Stanek, W K, Slotboom, D J
openaire +4 more sources
The human ATP-binding cassette (ABC) transporter superfamily [PDF]
Journal of Lipid Research, 2001 The transport of specific molecules across lipid membranes is an essential function of all living organisms and a large number of specific transporters have evolved to carry out this function.
Michael Dean +2 more
doaj +4 more sources
ATP-binding cassette transporter 13 mRNA expression level in schizophrenia patients [PDF]
Scientific Reports, 2020 The objective of this study was to investigate the expression and clinical role of ATP-binding cassette transporter 13 (ABCA13) gene previously shown to be associated with schizophrenia (SZ) through Genome-wide association studies studies.
Lu Qian +7 more
doaj +2 more sources
Aging Reduces ATP-Binding Cassette Transporter Expression in Brain Microvessels of Mice [PDF]
PharmaceuticalsBackground: ATP-binding cassette (ABC) transporters are expressed in the vascular walls of brain capillaries and remove toxic chemicals from the brain. The expression of ABC transporters in peripheral organs is transcriptionally regulated by clock genes ...
Yukiyo Wada +7 more
doaj +2 more sources
Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]
, 2006 ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Albers, Sonja-Verena, +5 more
core +14 more sources
Bixin and fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro
BMC Research Notes, 2021 Objective Cisplatin is a conventional anticancer drug that generates reactive oxygen species and causes apoptosis. However, many cancer cells develop alterations in the ATP binding cassette transporter responsible for the uptake and efflux process, which
Agustina Dwi Retno Nurcahyanti +2 more
doaj +1 more source
ATP‐binding cassette transporters in nonmodel plants [PDF]
New Phytologist, 2021 SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
openaire +2 more sources
Haematologica, 2012 ATP-binding cassette transporter (and specially P-glycoprotein) activity is a well known prognostic factor in acute myeloid leukemia, but when compared to other molecular markers its prognostic value has not been well studied. Here we study relationships
Pierre Hirsch +8 more
doaj +1 more source
Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR [PDF]
, 2017 The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that regulates the flow of anions across epithelia. Mutations in CFTR cause cystic fibrosis.
Corradi, V +3 more
core +1 more source