The human ATP-binding cassette (ABC) transporter superfamily [PDF]
Journal of Lipid Research, 2001 The transport of specific molecules across lipid membranes is an essential function of all living organisms and a large number of specific transporters have evolved to carry out this function.
Michael Dean +2 more
doaj +5 more sources
ATP-binding Cassette Transporter A7 (ABCA7) Loss of Function Alters Alzheimer Amyloid Processing [PDF]
Journal of Biological Chemistry, 2015 Background: The ATP-binding cassette transporter A7 (ABCA7) is a risk factor for sporadic Alzheimer disease (AD). Results: Loss of ABCA7 promoted Aβ processing and pathology in cell culture and AD mouse models.
Kenji Satô +4 more
openalex +2 more sources
ATP-binding cassette transporter 13 mRNA expression level in schizophrenia patients [PDF]
Scientific Reports, 2020 The objective of this study was to investigate the expression and clinical role of ATP-binding cassette transporter 13 (ABCA13) gene previously shown to be associated with schizophrenia (SZ) through Genome-wide association studies studies.
Lu Qian +7 more
doaj +2 more sources
Aging Reduces ATP-Binding Cassette Transporter Expression in Brain Microvessels of Mice [PDF]
PharmaceuticalsBackground: ATP-binding cassette (ABC) transporters are expressed in the vascular walls of brain capillaries and remove toxic chemicals from the brain. The expression of ABC transporters in peripheral organs is transcriptionally regulated by clock genes ...
Yukiyo Wada +7 more
doaj +2 more sources
Effects of ATP-binding cassette transporter G2 in extracellular vesicles on drug resistance of laryngeal cancer cells in in vivo and in vitro. [PDF]
Oncol Lett, 2021 Zhao Y, Chen Y, Wang J, Liu L.
europepmc +3 more sources
ATP-binding Cassette Transporter Defects and Their Roles in Hepatic Diseases [PDF]
J Clin Transl HepatolZhao D, Wu G.
europepmc +3 more sources
Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]
, 2006 ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Albers, Sonja-Verena, +5 more
core +14 more sources
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states
Proceedings of the National Academy of Sciences of the United States of America, 2013 Chitra A Shintre +2 more
exaly +2 more sources
Bixin and fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro
BMC Research Notes, 2021 Objective Cisplatin is a conventional anticancer drug that generates reactive oxygen species and causes apoptosis. However, many cancer cells develop alterations in the ATP binding cassette transporter responsible for the uptake and efflux process, which
Agustina Dwi Retno Nurcahyanti +2 more
doaj +1 more source
Haematologica, 2012 ATP-binding cassette transporter (and specially P-glycoprotein) activity is a well known prognostic factor in acute myeloid leukemia, but when compared to other molecular markers its prognostic value has not been well studied. Here we study relationships
Pierre Hirsch +8 more
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