Results 201 to 210 of about 59,687 (251)
The Mediator subunit SlMED25 and the co‐repressor SlSPX2 competitively bind the N‐terminal domain of the phosphate starvation response transcription factor SlPHR3 in tomato to form a sensitive molecular switch, which dynamically modulates phosphate starvation responses and maintains phosphate homeostasis, offering valuable targets for breeding low ...
Mingtong Zhai +10 more
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The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba +14 more
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The redox‐sensitive transcriptional repressor ZmMS1 coordinates reactive oxygen species homeostasis and lipid allocation for pollen exine and anther cuticle formation. Loss or precocious expression of ZmMS1 causes male sterility. Constitutive overexpression induces dwarfism and semi‐sterility. These findings enable flexible maize male‐sterility systems
Quancan Hou +13 more
wiley +1 more source
Herbivory triggers the production of green leaf volatiles, and dense planting results in induces increased concentration of linalool emission in maize canopies. These volatiles activate plant‐soil feedback that enriches beneficial rhizosphere bacteria, enhancing resistance, though sometimes at a growth cost, thereby offering new avenues for sustainable
Peiguo Yuan +3 more
wiley +1 more source
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ATP-Binding Cassette Transporters in the Heart
Trends in Cardiovascular Medicine, 2006Members of the ATP-binding cassette (ABC) protein superfamily are integral membrane proteins involved in energy-dependent transport of a wide variety of substrates across biologic membranes. ATP-binding cassette transporters serve as functional barriers against the entry of xenobiotics, for example, in the intestine or at the blood-brain barrier, or ...
Thomas F, Solbach +3 more
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ATP-binding cassette transporters and neurodegenerative diseases
Essays in Biochemistry, 2021Abstract ATP-binding cassette (ABC) transporters are one of the largest groups of transporter families in humans. ABC transporters mediate the translocation of a diverse range of substrates across cellular membranes, including amino acids, nucleosides, lipids, sugars and xenobiotics.
Jared S. Katzeff, Woojin Scott Kim
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ATP‐binding cassette transporters in liver
BioFactors, 2013AbstractThe human ATP‐binding cassette (ABC) superfamily consists of 48 members with 14 of them identified in normal human liver at the protein level. Most of the ABC members act as ATP dependent efflux transport systems. In the liver, ABC transporters are involved in diverse physiological processes including export of cholesterol, bile salts, and ...
Wlcek K, Stieger B
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ATP-Binding Cassette Transporters in Bacteria
Annual Review of Biochemistry, 2004▪ Abstract ATP-binding cassette (ABC) transporters couple ATP hydrolysis to the uptake and efflux of solutes across the cell membrane in bacteria and eukaryotic cells. In bacteria, these transporters are important virulence factors because they play roles in nutrient uptake and in secretion of toxins and antimicrobial agents. In humans, many diseases,
Amy L, Davidson, Jue, Chen
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ATP‐binding cassette transporters and cholesterol translocation
IUBMB Life, 2013AbstractCholesterol, a major component of mammalian cell membranes, plays important structural and functional roles. However, accumulation of excessive cholesterol is toxic to cells. Aberrant cholesterol trafficking and accumulation is the molecular basis for many diseases, such as atherosclerotic cardiovascular disease and Tangier's disease ...
Ge, Li, Hong-Mei, Gu, Da-Wei, Zhang
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ATP-binding cassette (ABC) transporters in atherosclerosis
Current Atherosclerosis Reports, 2002Macrophages play a central role in the initiation and progression of atherosclerotic lesions. In the nascent lesion, macrophages transform into foam cells through the excessive accumulation of cholesteryl esters. Dysfunctional lipid homeostasis in macrophages and foam cells ultimately results in the breakdown of membrane integrity and cell death ...
Gerd, Schmitz, Wolfgang E, Kaminski
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